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Tdark
TIGD6
Tigger transposable element-derived protein 6

Protein Summary
Description
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. [provided by RefSeq, Oct 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296736
  • ENSP00000296736
  • ENSG00000164296
  • ENST00000515406
  • ENSP00000425318
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.73
tissue
0.66
tissue sample
0.65
microRNA
0.61
protein domain
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.19   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 7   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.19   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 7   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
HERC1
Tbio
Family:  Enzyme
Novelty:  0.04318441
p_int:  0.999696188
p_ni:  0.000303812
Score:  0.188
Data Source:  BioPlex,STRINGDB
MTHFR
Tbio
Family:  Enzyme
Novelty:  0.00018162
p_int:  0.999367307
p_ni:  0.000632693
Score:  0.248
Data Source:  BioPlex,STRINGDB
GTF2I
Tbio
Family:  TF
Novelty:  0.00703345
p_int:  0.995834434
p_ni:  0.004165566
Score:  0.306
Data Source:  BioPlex,STRINGDB
ZNF681
Tdark
Family:  TF
Novelty:  3.00740001
Score:  0.582
Data Source:  STRINGDB
ALG1L2
Tdark
Family:  Enzyme
Novelty:  4.14027879
Score:  0.559
Data Source:  STRINGDB
ZNF648
Tdark
Family:  TF
Novelty:  0.57586282
Score:  0.54
Data Source:  STRINGDB
ZRANB2
Tbio
Novelty:  0.06105086
Score:  0.519
Data Source:  STRINGDB
CCDC97
Tdark
Novelty:  2.36351796
Score:  0.519
Data Source:  STRINGDB
OR52N4
Tdark
Family:  oGPCR
Novelty:  2.21267737
Score:  0.506
Data Source:  STRINGDB
MAD2L1
Tbio
Novelty:  0.01623659
Score:  0.486
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte percentage of leukocytes
2
6
6
98.8
monocyte count
1
2
2
87.1
granulocyte percentage of myeloid white cells
1
2
2
85.2
neutrophil percentage of leukocytes
1
1
1
68.8
mean reticulocyte volume
1
1
1
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte percentage of leukocytes
6
98.8
monocyte count
2
87.1
granulocyte percentage of myeloid white cells
2
85.2
neutrophil percentage of leukocytes
1
68.8
mean reticulocyte volume
1
49.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tigger transposable element derived 6
VGNC:4197
462185
Macaque
tigger transposable element derived 6
710090
Dog
tigger transposable element derived 6
VGNC:47373
100856203
Horse
tigger transposable element derived 6
VGNC:24105
100071686
Opossum
tigger transposable element derived 6
100619610
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tigger transposable element derived 6
Macaque
tigger transposable element derived 6
Dog
tigger transposable element derived 6
Horse
tigger transposable element derived 6
Opossum
tigger transposable element derived 6
Publication Statistics
PubMed Score 0.19
PubMed score by year
PubTator Score 0.03
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title