Tbio THY1 Thy-1 membrane glycoprotein

Protein Summary

Description

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

Uniprot Accession IDs

• P04216
• Q16008
• Q9NSP1

Gene Name

• THY1

Ensembl ID

• ENST00000284240
• ENSP00000284240
• ENSG00000154096
• ENST00000528522
• ENSP00000431301

Symbol

• CD90
• CDw90

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0.96
cellular component	0.95
PubMedID	0.93
gene perturbation	0.91
molecular function	0.84

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3283.81   (req: < 5)

Gene RIFs: 98   (req: <= 3)

Antibodies: 1867   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3283.81   (req: >= 5)

Gene RIFs: 98   (req: > 3)

Antibodies: 1867   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 28

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0