Tdark THEG Testicular haploid expressed gene protein

Protein Summary

Description

May be involved (but not essential) in spermatogenesis. This gene is specifically expressed in the nucleus of haploid male germ cells. The orthologous gene in mice encodes a protein that may play a role in protein assembly through interactions with T-complex protein 1 subunit epsilon. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Uniprot Accession IDs

• Q9P2T0
• A6NMJ8

Gene Name

• THEG

Ensembl ID

• ENST00000342640
• ENSP00000340088
• ENSG00000105549
• ENST00000346878
• ENSP00000264820

Symbol

• CT56
• THEG1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.56
cell type or tissue	0.52
gene perturbation	0.49
cell line	0.44
tissue	0.43

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.32   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 44   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.32   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 44   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0