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Tdark
THAP8
THAP domain-containing protein 8

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000292894
  • ENSP00000292894
  • ENSG00000161277
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.74
cell type or tissue
0.56
tissue sample
0.54
transcription factor binding site profile
0.53
cellular component
0.52


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.15   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.15   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (13)
PRMT7
Tchem
Family:  Epigenetic
Novelty:  0.02310897
p_int:  0.999805583
p_ni:  0.000166063
p_wrong:  0.000028353
Score:  0.513
Data Source:  BioPlex,STRINGDB
UBE2D2
Tbio
Novelty:  0.00603877
p_int:  0.990673703
p_ni:  0.007664203
p_wrong:  0.001662094
Score:  0.219
Data Source:  BioPlex,STRINGDB
LASP1
Tbio
Novelty:  0.00960538
p_int:  0.964925441
p_ni:  0.035074558
p_wrong:  1e-9
Score:  0.237
Data Source:  BioPlex,STRINGDB
C9orf16
Tdark
Novelty:  1.20658855
p_int:  0.944697392
p_ni:  0.000027499
p_wrong:  0.055275109
Score:  0.534
Data Source:  BioPlex,STRINGDB
ANKRD18B
Tdark
Novelty:  0.64962094
Score:  0.669
Data Source:  STRINGDB
THAP6
Tdark
Family:  TF
Novelty:  3.35556738
Score:  0.669
Data Source:  STRINGDB
THAP10
Tdark
Family:  TF
Novelty:  1.06994665
Score:  0.669
Data Source:  STRINGDB
THAP11
Tbio
Family:  TF
Novelty:  0.0679686
Score:  0.609
Data Source:  STRINGDB
THAP9
Tbio
Family:  TF
Novelty:  0.25915023
Score:  0.583
Data Source:  STRINGDB
SLF1
Tbio
Novelty:  0.04904367
Score:  0.553
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
21.5
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
THAP domain containing 8
712281
Dog
THAP domain containing 8
VGNC:47332
100688093
Cow
THAP domain containing 8
VGNC:35825
537311
Species
Name
OMA
EggNOG
Inparanoid
Macaque
THAP domain containing 8
Dog
THAP domain containing 8
Cow
THAP domain containing 8
Publication Statistics
PubMed Score 0.15
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title