You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
THADA
Thyroid adenoma-associated protein

Protein Summary
Description
This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000402360
  • ENSP00000385441
  • ENSG00000115970
  • ENST00000404790
  • ENSP00000384266
  • ENST00000405006
  • ENSP00000385995
  • ENST00000405975
  • ENSP00000386088

Symbol
  • GITA
  • KIAA1767
  • GITA
  • ARMC13
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
phenotype
0.94
histone modification site profile
0.91
transcription factor binding site profile
0.91
trait
0.86
transcription factor
0.71


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.16   (req: < 5)
Gene RIFs: 22   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.16   (req: >= 5)
Gene RIFs: 22   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (153)
CYB5B
Tbio
Novelty:  0.09395308
p_int:  0.999899664
p_ni:  0.000100336
Data Source:  BioPlex
VSIG2
Tdark
Novelty:  0.32398032
p_int:  0.999834693
p_ni:  0.000165307
Score:  0.182
Data Source:  BioPlex,STRINGDB
OPALIN
Tdark
Novelty:  0.08221612
p_int:  0.999825423
p_ni:  0.000174577
Data Source:  BioPlex
VASN
Tbio
Novelty:  0.05424159
p_int:  0.999712967
p_ni:  0.000287033
Data Source:  BioPlex
TMEM206
Tdark
Novelty:  0.17311172
p_int:  0.999518696
p_ni:  0.000481304
Data Source:  BioPlex
TNFRSF1A
Tchem
Novelty:  0.00037847
p_int:  0.998862631
p_ni:  0.001137369
Data Source:  BioPlex
CD226
Tbio
Novelty:  0.00374102
p_int:  0.998656645
p_ni:  0.001343355
Data Source:  BioPlex
OPRM1
Tclin
Family:  GPCR
Novelty:  0.0003701
p_int:  0.99831819
p_ni:  0.00168181
Data Source:  BioPlex
C11orf87
Tdark
Novelty:  1.33249342
p_int:  0.991033049
p_ni:  0.008966951
Data Source:  BioPlex
CD274
Tclin
Novelty:  0.00013449
p_int:  0.990061959
p_ni:  0.009938041
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Metabolism of RNA (R-HSA-8953854)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of RNA
Reactome
tRNA modification in the nucleus and cytosol
Reactome
tRNA processing
Name
Explore in Pharos
Explore in Source
Metabolism of RNA
tRNA modification in the nucleus and cytosol
tRNA processing
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (66)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
12
11
3
1.1
98.6
lymphocyte percentage of leukocytes
2
3
3
97.3
neutrophil percentage of leukocytes
2
3
3
97.2
platelet count
3
3
2
3.6
96.9
neutrophil count
3
3
3
94.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
3
1.1
98.6
lymphocyte percentage of leukocytes
3
97.3
neutrophil percentage of leukocytes
3
97.2
platelet count
2
3.6
96.9
neutrophil count
3
94.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
THADA, armadillo repeat containing
VGNC:10289
737308
Macaque
THADA, armadillo repeat containing
716361
Mouse
MGI:3039623
240174
Rat
RGD:1560519
313865
Dog
THADA, armadillo repeat containing
VGNC:47323
100126180
Species
Name
OMA
EggNOG
Inparanoid
Chimp
THADA, armadillo repeat containing
Macaque
THADA, armadillo repeat containing
Mouse
Rat
Dog
THADA, armadillo repeat containing
Publication Statistics
PubMed Score 13.16
PubMed score by year
PubTator Score 34.94
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title