THADA
Thyroid adenoma-associated protein
Protein Summary
This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
- ENST00000402360
- ENSP00000385441
- ENSG00000115970
- ENST00000404790
- ENSP00000384266
- ENST00000405006
- ENSP00000385995
- ENST00000405975
- ENSP00000386088
- GITA
- KIAA1767
- GITA
- ARMC13
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
phenotype | 0.94 | ||
histone modification site profile | 0.91 | ||
transcription factor binding site profile | 0.91 | ||
trait | 0.86 | ||
transcription factor | 0.71 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 17.88 (req: < 5)
Gene RIFs: 28 (req: <= 3)
Antibodies: 100 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 17.88 (req: >= 5)
Gene RIFs: 28 (req: > 3)
Antibodies: 100 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0