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Tdark
TGIF2LY
Homeobox protein TGIF2LY

Protein Summary
Description
May have a transcription role in testis. May act as a competitor/regulator of TGIF2LX. This gene encodes a member of the TALE/TGIF homeobox family of transcription factors. This gene lies within the male specific region of chromosome Y, in a block of sequence that is thought to be the result of a large X-to-Y transposition. The C-terminus of this protein is divergent from that of its chromosome X homolog (TGIF2LX), suggesting that this protein may act as a regulator of TGIF2LX. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000321217
  • ENSP00000318502
  • ENSG00000176679
  • ENST00000559055
  • ENSP00000453750

Symbol
  • TGIFLY
  • TGIFLY
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0.41
protein domain
0.41
tissue
0.41
interacting protein
0.35
biological term
0.34


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 93   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 93   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
TGIF2LX
Tbio
Family:  TF
Novelty:  0.10755032
p_int:  0.999999999
p_wrong:  1e-9
Data Source:  BioPlex
LRP6
Tbio
Novelty:  0.00305615
p_int:  0.999944524
p_ni:  0.000055476
Data Source:  BioPlex
PDCD4
Tchem
Novelty:  0.00213303
p_int:  0.999899173
p_ni:  0.000038658
p_wrong:  0.00006217
Data Source:  BioPlex
ANKHD1
Tbio
Novelty:  0.05390096
p_int:  0.999876528
p_ni:  0.000123471
p_wrong:  1e-9
Data Source:  BioPlex
OGFR
Tbio
Novelty:  0.01046109
p_int:  0.999857096
p_ni:  0.000142904
Data Source:  BioPlex
CRBN
Tclin
Novelty:  0.00385433
p_int:  0.999460339
p_ni:  0.000447661
p_wrong:  0.000092001
Data Source:  BioPlex
AHCYL2
Tbio
Family:  Enzyme
Novelty:  0.08695339
p_int:  0.999164081
p_ni:  0.000835919
Data Source:  BioPlex
PGP
Tbio
Family:  Enzyme
Novelty:  0.0225528
p_int:  0.998841344
p_ni:  0.001158655
p_wrong:  1e-9
Data Source:  BioPlex
GMNN
Tbio
Novelty:  0.00436572
p_int:  0.998825485
p_ni:  0.001174501
p_wrong:  1.5e-8
Data Source:  BioPlex
DCAF16
Tdark
Novelty:  0.35666992
p_int:  0.998506923
p_ni:  0.001482348
p_wrong:  0.000010728
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubTator Score 1.33
PubTator score by year
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Related Publications
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PMID
Year
Title