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Tbio
TGIF2LX
Homeobox protein TGIF2LX

Protein Summary
Description
May have a transcription role in testis. This gene encodes a member of the TALE/TGIF homeobox family of transcription factors. Testis-specific expression suggests that this gene may play a role in spermatogenesis. A homolog of this gene lies within the male specific region of chromosome Y, in a block of sequence that is thought to be the result of a large X-to-Y transposition. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000283891
  • ENSP00000355119
  • ENSG00000153779
  • ENST00000561129
  • ENSP00000453704

Symbol
  • TGIFLX
  • TGIFLX
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.51
cell type or tissue
0.49
tissue
0.46
biological process
0.41
protein domain
0.41


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.93   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 118   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.93   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 118   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
TGIF2LY
Tdark
Family:  TF
p_int:  0.999999999
p_wrong:  1e-9
Data Source:  BioPlex
DKK2
Tbio
Novelty:  0.01445201
p_int:  0.999999496
p_ni:  5e-7
p_wrong:  4e-9
Data Source:  BioPlex
PABPC5
Tdark
Novelty:  0.36077159
Score:  0.906
Data Source:  STRINGDB
TGFBI
Tbio
Novelty:  0.00154768
Score:  0.8
Data Source:  STRINGDB
PCDH11X
Tbio
Novelty:  0.00588287
Score:  0.745
Data Source:  STRINGDB
ESX1
Tbio
Family:  TF
Novelty:  0.00330753
Score:  0.714
Data Source:  STRINGDB
RHOXF2
Tbio
Family:  TF
Novelty:  0.15342928
Score:  0.685
Data Source:  STRINGDB
CDYL2
Tchem
Family:  Epigenetic
Novelty:  0.11630883
Score:  0.654
Data Source:  STRINGDB
CCDC124
Tdark
Novelty:  0.72482697
Score:  0.626
Data Source:  STRINGDB
PARPBP
Tbio
Novelty:  0.0886089
Score:  0.625
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
TGFB-induced factor homeobox 2-like, X-linked
450174
Macaque
TGFB induced factor homeobox 2 like, X-linked
574239
Mouse
MGI:3800824
100039551
Rat
RGD:1561826
367885
Dog
TGFB induced factor homeobox 2 like, X-linked
492001
Species
Name
OMA
EggNOG
Inparanoid
Chimp
TGFB-induced factor homeobox 2-like, X-linked
Macaque
TGFB induced factor homeobox 2 like, X-linked
Mouse
Rat
Dog
TGFB induced factor homeobox 2 like, X-linked
Publication Statistics
PubMed Score 9.93
PubMed score by year
PubTator Score 7.33
PubTator score by year
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Related Publications
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PMID
Year
Title