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Tdark
TEX35
Testis-expressed protein 35

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000319416
  • ENSP00000323795
  • ENSG00000240021
  • ENST00000367639
  • ENSP00000356611
  • ENST00000367641
  • ENSP00000356613
  • ENST00000367643
  • ENSP00000356615

Symbol
  • C1orf49
  • TSC24
  • C1orf49
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.59
cell line
0.56
cell type or tissue
0.56
cellular component
0.56
tissue sample
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.57   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 84   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.57   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 84   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (44)
BORCS7
Tbio
Novelty:  0.14135922
p_int:  0.999999647
p_ni:  3.31e-7
p_wrong:  2.2e-8
Score:  0.202
Data Source:  BioPlex,STRINGDB
BORCS5
Tdark
Novelty:  0.59333419
p_int:  0.999995869
p_ni:  0.000004131
Score:  0.173
Data Source:  BioPlex,STRINGDB
DTNBP1
Tbio
Novelty:  0.00341619
p_int:  0.999929755
p_ni:  0.000070245
Score:  0.159
Data Source:  BioPlex,STRINGDB
BLOC1S1
Tbio
Novelty:  0.02921036
p_int:  0.999898537
p_ni:  0.000101414
p_wrong:  4.9e-8
Score:  0.653
Data Source:  BioPlex,STRINGDB
GOLGA2
Tbio
Novelty:  0.00544771
p_int:  0.99959951
p_ni:  0.00040049
Data Source:  BioPlex
PLCD1
Tchem
Family:  Enzyme
Novelty:  0.00742197
p_int:  0.999484001
p_ni:  0.000515957
p_wrong:  4.2e-8
Data Source:  BioPlex
BLOC1S2
Tbio
Novelty:  0.02346362
p_int:  0.998980243
p_ni:  0.001019363
p_wrong:  3.94e-7
Score:  0.539
Data Source:  BioPlex,STRINGDB
CALHM4
Tdark
Family:  IC
Novelty:  2.79788039
p_int:  0.998742578
p_ni:  0.001257326
p_wrong:  9.6e-8
Score:  0.191
Data Source:  BioPlex,STRINGDB
LYG2
Tbio
Family:  Enzyme
Novelty:  0.12091256
p_int:  0.998093735
p_ni:  0.001906265
Data Source:  BioPlex
DSG4
Tbio
Novelty:  0.01599371
p_int:  0.996492552
p_ni:  0.003507448
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
6
3
10
87
serum gamma-glutamyl transferase measurement
2
2
2
83
red blood cell distribution width
2
2
2
67.3
apolipoprotein A 1 measurement
1
1
1
63.1
triglyceride measurement
1
1
1
33.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
10
87
serum gamma-glutamyl transferase measurement
2
83
red blood cell distribution width
2
67.3
apolipoprotein A 1 measurement
1
63.1
triglyceride measurement
1
33.1
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
testis expressed 35
VGNC:10936
457548
Macaque
testis expressed 35
717255
Mouse
MGI:1920685
73435
Rat
RGD:1595460
680164
Dog
testis expressed 35
VGNC:47275
610944
Species
Name
OMA
EggNOG
Inparanoid
Chimp
testis expressed 35
Macaque
testis expressed 35
Mouse
Rat
Dog
testis expressed 35
Publication Statistics
PubMed Score 1.57
PubMed score by year
PubTator Score 3.59
PubTator score by year
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Related Publications
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PMID
Year
Title