TET2
Methylcytosine dioxygenase TET2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.88 | ||
biological term | 0.85 | ||
microRNA | 0.83 | ||
transcription factor | 0.78 | ||
transcription factor perturbation | 0.74 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Epigenetic regulation of gene expression | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | TET1,2,3 and TDG demethylate DNA | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Epigenetic regulation of gene expression | ||||
Gene expression (Transcription) | ||||
TET1,2,3 and TDG demethylate DNA | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
intelligence | 7 | 21 | 11 | 6.4 | 93.5 | ||||
lymphocyte count | 4 | 3 | 4 | 93.5 | |||||
7 | 3 | 1 | 1.1 | 93.2 | |||||
self reported educational attainment | 5 | 5 | 4 | 6.9 | 93 | ||||
body height | 3 | 3 | 3 | 92.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
intelligence | 11 | 6.4 | 93.5 | ||||
lymphocyte count | 4 | 93.5 | |||||
1 | 1.1 | 93.2 | |||||
self reported educational attainment | 4 | 6.9 | 93 | ||||
body height | 3 | 92.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | tet methylcytosine dioxygenase 2 | VGNC:730 | 471263 | |||||
Mouse | MGI:2443298 | 214133 | ||||||
Rat | RGD:1311625 | 310859 | ||||||
Dog | tet methylcytosine dioxygenase 2 | VGNC:47261 | 478499 | |||||
Cow | tet methylcytosine dioxygenase 2 | VGNC:35757 | 538481 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | tet methylcytosine dioxygenase 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | tet methylcytosine dioxygenase 2 | |||||
Cow | tet methylcytosine dioxygenase 2 | |||||
PMID | Year | Title |
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