TET1
Methylcytosine dioxygenase TET1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.84 | ||
microRNA | 0.79 | ||
gene perturbation | 0.68 | ||
molecular function | 0.67 | ||
cell line | 0.56 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Epigenetic regulation of gene expression | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | TET1,2,3 and TDG demethylate DNA | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Epigenetic regulation of gene expression | ||||
Gene expression (Transcription) | ||||
TET1,2,3 and TDG demethylate DNA | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
HbA1c measurement | 1 | 1 | 1 | 81.6 | |||||
2 | 2 | 2 | 76.7 | ||||||
BMI-adjusted hip circumference | 2 | 6 | 6 | 71.4 | |||||
body height | 1 | 1 | 1 | 68.8 | |||||
triglyceride measurement | 1 | 1 | 1 | 33.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
HbA1c measurement | 1 | 81.6 | |||||
2 | 76.7 | ||||||
BMI-adjusted hip circumference | 6 | 71.4 | |||||
body height | 1 | 68.8 | |||||
triglyceride measurement | 1 | 33.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | tet methylcytosine dioxygenase 1 | VGNC:7268 | 450497 | |||||
Macaque | tet methylcytosine dioxygenase 1 | 693707 | ||||||
Mouse | MGI:1098693 | 52463 | ||||||
Rat | RGD:1310993 | 309902 | ||||||
Dog | tet methylcytosine dioxygenase 1 | VGNC:47260 | 479229 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | tet methylcytosine dioxygenase 1 | |||||
Macaque | tet methylcytosine dioxygenase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | tet methylcytosine dioxygenase 1 | |||||
PMID | Year | Title |
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