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Tdark
TEPP
Testis, prostate and placenta-expressed protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000290871
  • ENSP00000290871
  • ENSG00000159648
  • ENST00000441824
  • ENSP00000401917
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.64
cell line
0.62
gene perturbation
0.59
tissue
0.55
tissue sample
0.48


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.56   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 6   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.56   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 6   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (14)
HSPA5
Tchem
Novelty:  0.00043424
p_int:  0.785320098
p_ni:  0.214679902
Score:  0.188
Data Source:  BioPlex,STRINGDB
PKM
Tchem
Family:  Kinase
Novelty:  0.00076567
Score:  0.648
Data Source:  STRINGDB
CCDC80
Tbio
Novelty:  0.01634056
Score:  0.626
Data Source:  STRINGDB
RAB35
Tbio
Family:  Enzyme
Novelty:  0.01514601
Score:  0.579
Data Source:  STRINGDB
ODF3
Tbio
Novelty:  0.08747036
Score:  0.535
Data Source:  STRINGDB
RAB37
Tbio
Family:  Enzyme
Novelty:  0.07133253
Score:  0.527
Data Source:  STRINGDB
CT45A6
Tdark
Novelty:  0.32451689
Score:  0.511
Data Source:  STRINGDB
SPAG8
Tbio
Novelty:  0.06962141
Score:  0.502
Data Source:  STRINGDB
ATAD3C
Tdark
Family:  Enzyme
Novelty:  0.33587655
Score:  0.491
Data Source:  STRINGDB
BCHE
Tclin
Family:  Enzyme
Novelty:  0.00031267
Score:  0.478
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum gamma-glutamyl transferase measurement
2
2
2
91.9
FEV/FEC ratio
1
1
1
82.1
serum alanine aminotransferase measurement
1
1
0
6.4
44.2
1
2
0
1.1
26.6
pulmonary function measurement
1
1
1
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum gamma-glutamyl transferase measurement
2
91.9
FEV/FEC ratio
1
82.1
serum alanine aminotransferase measurement
0
6.4
44.2
0
1.1
26.6
pulmonary function measurement
1
15.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
testis, prostate and placenta expressed
738259
Macaque
testis, prostate and placenta expressed
706183
Mouse
MGI:1920657
73407
Rat
RGD:735198
291850
Dog
testis, prostate and placenta expressed
VGNC:47250
100685911
Species
Name
OMA
EggNOG
Inparanoid
Chimp
testis, prostate and placenta expressed
Macaque
testis, prostate and placenta expressed
Mouse
Rat
Dog
testis, prostate and placenta expressed
Publication Statistics
PubMed Score 6.56
PubMed score by year
PubTator Score 9.00
PubTator score by year
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Related Publications
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PMID
Year
Title