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Tbio
TENT5D
Terminal nucleotidyltransferase 5D

Protein Summary
Description
Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase. Antibodies against the protein encoded by this gene were found only in plasma from cancer patients. While it may be a target for immunotherapy, the function of this gene is unknown. [provided by RefSeq, Dec 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000308293
  • ENSP00000308575
  • ENSG00000174016
  • ENST00000538312
  • ENSP00000443410

Symbol
  • FAM46D
  • CT112
  • CT1.26
  • FAM46D
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.65
microRNA
0.58
cell line
0.53
trait
0.46
transcription factor
0.42


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.86   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 72   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.86   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0