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Tbio
TEKT4
Tektin-4

Protein Summary
Description
May be a structural component of the sperm flagellum. Contributes to normal sperm motility.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295201
  • ENSP00000295201
  • ENSG00000163060
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.6
gene perturbation
0.56
cellular component
0.53
cell line
0.47
cell type or tissue
0.42


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.09   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 161   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.09   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
NEK1
Tchem
Family:  Kinase
Novelty:  0.0164923
p_int:  0.999999299
p_ni:  7.01e-7
Score:  0.218
Data Source:  BioPlex,STRINGDB
CRY1
Tchem
Novelty:  0.00116593
p_int:  0.999990895
p_ni:  0.000009105
Score:  0.552
Data Source:  BioPlex,STRINGDB
CRY2
Tbio
Novelty:  0.00156961
p_int:  0.99998127
p_ni:  0.000018725
p_wrong:  5e-9
Score:  0.71
Data Source:  BioPlex,STRINGDB
CFAP410
Tbio
Novelty:  0.0143773
p_int:  0.999924815
p_ni:  0.000075134
p_wrong:  5.2e-8
Score:  0.239
Data Source:  BioPlex,STRINGDB
CLOCK
Tbio
Family:  TF; Epigenetic
Novelty:  0.00159625
p_int:  0.999683425
p_ni:  0.000249772
p_wrong:  0.000066803
Score:  0.211
Data Source:  BioPlex,STRINGDB
COG2
Tbio
Novelty:  0.03109287
p_int:  0.997124696
p_ni:  0.002875304
Score:  0.175
Data Source:  BioPlex,STRINGDB
ABRAXAS1
Tbio
Novelty:  0.07078408
p_int:  0.995758664
p_ni:  0.000045505
p_wrong:  0.004195832
Score:  0.188
Data Source:  BioPlex,STRINGDB
ADSL
Tbio
Family:  Enzyme
Novelty:  0.0028496
p_int:  0.979724116
p_ni:  0.020275881
p_wrong:  3e-9
Score:  0.204
Data Source:  BioPlex,STRINGDB
NDE1
Tbio
Novelty:  0.00567438
p_int:  0.905395316
p_ni:  0.094604684
Score:  0.196
Data Source:  BioPlex,STRINGDB
COG4
Tbio
Novelty:  0.03809668
p_int:  0.807822839
p_ni:  0.192177161
Score:  0.177
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1919090
71840
Rat
RGD:1308075
302991
Horse
tektin-4
100067446
Cow
tektin 4
510343
Chicken
tektin 4
CGNC:3904
416527
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Horse
tektin-4
Cow
tektin 4
Chicken
tektin 4
Publication Statistics
PubMed Score 22.09
PubMed score by year
PubTator Score 6.93
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title