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Tbio
TEKT3
Tektin-3

Protein Summary
Description
May be a structural component of the sperm flagellum. Required for normal sperm mobility. This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000338696
  • ENSP00000343995
  • ENSG00000125409
  • ENST00000395930
  • ENSP00000379263
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.75
cell type or tissue
0.65
histone modification site profile
0.57
tissue sample
0.55
tissue
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.74   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 129   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.74   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 129   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (54)
CLUH
Tbio
Novelty:  0.14027296
p_int:  0.998287003
p_ni:  0.001712997
Score:  0.159
Data Source:  BioPlex,STRINGDB
LIMD1
Tbio
Novelty:  0.04868333
p_int:  0.997053254
p_ni:  0.002946255
p_wrong:  4.92e-7
Score:  0.159
Data Source:  BioPlex,STRINGDB
ZNF703
Tbio
Novelty:  0.03956045
p_int:  0.940107732
p_ni:  0.059892268
Score:  0.171
Data Source:  BioPlex,STRINGDB
TYSND1
Tbio
Family:  Enzyme
Novelty:  0.16036122
p_int:  0.930594768
p_ni:  0.069405232
Score:  0.345
Data Source:  BioPlex,STRINGDB
PITRM1
Tchem
Family:  Enzyme
Novelty:  0.08067518
p_int:  0.867494196
p_ni:  0.132505804
Score:  0.199
Data Source:  BioPlex,STRINGDB
PRRC2A
Tbio
Novelty:  0.01493149
p_int:  0.758714729
p_ni:  0.241283933
p_wrong:  0.000001337
Score:  0.189
Data Source:  BioPlex,STRINGDB
ROPN1L
Tbio
Novelty:  0.18077695
Score:  0.7
Data Source:  STRINGDB
CCDC63
Tbio
Novelty:  0.11520913
Score:  0.657
Data Source:  STRINGDB
CFAP36
Tdark
Novelty:  0.42842118
Score:  0.641
Data Source:  STRINGDB
CD164L2
Tdark
Novelty:  0.83369268
Score:  0.639
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
premature birth
1
1
0
1.1
7.3
parental genotype effect measurement
1
1
0
1.1
7.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
premature birth
0
1.1
7.3
parental genotype effect measurement
0
1.1
7.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tektin 3
VGNC:9686
455052
Macaque
tektin 3
693793
Mouse
MGI:1918312
71062
Rat
RGD:1310582
287392
Dog
tektin 3
VGNC:47243
479510
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tektin 3
Macaque
tektin 3
Mouse
Rat
Dog
tektin 3
Publication Statistics
PubMed Score 18.74
PubMed score by year
PubTator Score 2.67
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title