TDP1
Tyrosyl-DNA phosphodiesterase 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.86 | ||
kinase perturbation | 0.81 | ||
transcription factor binding site profile | 0.69 | ||
molecular function | 0.67 | ||
tissue | 0.64 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | DNA Double-Strand Break Repair | ||||
Reactome | DNA Repair | ||||
Reactome | Nonhomologous End-Joining (NHEJ) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
DNA Double-Strand Break Repair | ||||
DNA Repair | ||||
Nonhomologous End-Joining (NHEJ) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
1 | 1 | 0 | 2.2 | 46.1 | |||||
1 | 1 | 0 | 2.3 | 36.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 2.2 | 46.1 | |||||
0 | 2.3 | 36.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | tyrosyl-DNA phosphodiesterase 1 | VGNC:6768 | 453096 | |||||
Macaque | tyrosyl-DNA phosphodiesterase 1 | 695338 | ||||||
Mouse | MGI:1920036 | 104884 | ||||||
Rat | RGD:1309618 | 314380 | ||||||
Dog | tyrosyl-DNA phosphodiesterase 1 | VGNC:47218 | 490828 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | tyrosyl-DNA phosphodiesterase 1 | |||||
Macaque | tyrosyl-DNA phosphodiesterase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | tyrosyl-DNA phosphodiesterase 1 | |||||
PMID | Year | Title |
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