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Tbio
TCTEX1D4
Tctex1 domain-containing protein 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339355
  • ENSP00000341803
  • ENSG00000188396
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.84
cellular component
0.68
tissue sample
0.6
histone modification site profile
0.59
transcription factor
0.56


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.8   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 60   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.8   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
TCTEX1D2
Tbio
Novelty:  0.15075459
p_int:  0.999999614
p_ni:  2.66e-7
p_wrong:  1.2e-7
Score:  0.174
Data Source:  BioPlex,STRINGDB
TRO
Tbio
Novelty:  0.02850833
p_int:  0.999978926
p_ni:  0.000021074
Data Source:  BioPlex
WDR60
Tbio
Novelty:  0.13020561
p_int:  0.999824836
p_ni:  0.000175162
p_wrong:  2e-9
Score:  0.499
Data Source:  BioPlex,STRINGDB
ABHD17B
Tbio
Family:  Enzyme
Novelty:  0.64360453
p_int:  0.994759366
p_ni:  0.005130809
p_wrong:  0.000109825
Data Source:  BioPlex
WDR34
Tbio
Novelty:  0.05515847
p_int:  0.96596189
p_ni:  0.03403811
Score:  0.48
Data Source:  BioPlex,STRINGDB
C2CD5
Tbio
Novelty:  0.40144687
p_int:  0.855712694
p_ni:  0.11807605
p_wrong:  0.026211256
Data Source:  BioPlex
HSPA14
Tbio
Novelty:  0.01714625
p_int:  0.770723128
p_ni:  0.229276328
p_wrong:  5.43e-7
Data Source:  BioPlex
DYNLT1
Tbio
Novelty:  0.00336045
Score:  0.872
Data Source:  STRINGDB
ENG
Tbio
Novelty:  0.00036729
Score:  0.836
Data Source:  STRINGDB
WDR63
Tdark
Novelty:  0.04141617
Score:  0.687
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
intraocular pressure measurement
1
1
0
7
54.4
red blood cell distribution width
1
1
1
53.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
intraocular pressure measurement
0
7
54.4
red blood cell distribution width
1
53.7
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
Tctex1 domain containing 4
VGNC:1668
456545
Macaque
Tctex1 domain containing 4
704192
Mouse
MGI:3045358
242646
Rat
RGD:1565942
102551208
Dog
Tctex1 domain containing 4
VGNC:47212
482520
Species
Name
OMA
EggNOG
Inparanoid
Chimp
Tctex1 domain containing 4
Macaque
Tctex1 domain containing 4
Mouse
Rat
Dog
Tctex1 domain containing 4
Publication Statistics
PubMed Score 2.80
PubMed score by year
PubTator Score 2.33
PubTator score by year
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Related Publications
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PMID
Year
Title