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Tdark
TCTE3
Tctex1 domain-containing protein 3

Protein Summary
Description
May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366774
  • ENSP00000355736
  • ENSG00000184786
  • ENST00000610291
  • ENSP00000478684
  • ENSG00000275368

Symbol
  • TCTEX1D3
  • TCTEX1D3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
transcription factor binding site profile
0.78
cell type or tissue
0.76
transcription factor perturbation
0.54
cellular component
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.1   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 24   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.1   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 24   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (126)
DYNLL2
Tbio
Novelty:  0.11209457
Score:  0.976
Data Source:  STRINGDB
DYNC2LI1
Tbio
Novelty:  0.05087433
Score:  0.947
Data Source:  STRINGDB
DYNLRB2
Tbio
Novelty:  0.1714161
Score:  0.946
Data Source:  STRINGDB
DYNLL1
Tbio
Novelty:  0.00397334
Score:  0.944
Data Source:  STRINGDB
DYNLRB1
Tbio
Novelty:  0.01342103
Score:  0.942
Data Source:  STRINGDB
WDR60
Tbio
Novelty:  0.13020561
Score:  0.939
Data Source:  STRINGDB
WDR34
Tbio
Novelty:  0.05515847
Score:  0.938
Data Source:  STRINGDB
TCTEX1D1
Tdark
Novelty:  1.09622578
Score:  0.926
Data Source:  STRINGDB
TCTEX1D2
Tbio
Novelty:  0.15075459
Score:  0.913
Data Source:  STRINGDB
IFT88
Tbio
Novelty:  0.00727114
Score:  0.912
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Cilium Assembly (R-HSA-5617833)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cilium Assembly
Reactome
Intraflagellar transport
Reactome
Organelle biogenesis and maintenance
Name
Explore in Pharos
Explore in Source
Cilium Assembly
Intraflagellar transport
Organelle biogenesis and maintenance
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (4)
Items per page:
1 – 4 of 4
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1
1
44.2
self reported educational attainment
1
1
1
44.2
smoking status measurement
1
1
1
24.5
smoking status measurement
1
1
1
24.5
Items per page:
1 – 4 of 4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
44.2
self reported educational attainment
1
44.2
smoking status measurement
1
24.5
smoking status measurement
1
24.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
t-complex-associated-testis-expressed 3
738036
Macaque
t-complex-associated-testis-expressed 3 [Source:HGNC Symbol;Acc:HGNC:11695]
Mouse
MGI:3809205
100041639
Mouse
MGI:98642
21647
Rat
RGD:1310947
365153
Species
Name
OMA
EggNOG
Inparanoid
Chimp
t-complex-associated-testis-expressed 3
Macaque
t-complex-associated-testis-expressed 3 [Source:HGNC Symbol;Acc:HGNC:11695]
Mouse
Mouse
Rat
Publication Statistics
PubMed Score 7.10
PubMed score by year
PubTator Score 3.41
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title