You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
TCP11L2
T-complex protein 11-like protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000299045
  • ENSP00000299045
  • ENSG00000166046
  • ENST00000547153
  • ENSP00000448952
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.79
transcription factor binding site profile
0.79
gene perturbation
0.74
disease
0.65
tissue sample
0.64


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.78   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 214   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.78   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 214   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (45)
TUBA1B
Tchem
Novelty:  0.02465964
p_int:  0.999999611
p_ni:  3.89e-7
Score:  0.753
Data Source:  BioPlex,STRINGDB
TUBA3C
Tchem
Novelty:  0.0187396
p_int:  0.999999372
p_ni:  6.28e-7
Score:  0.641
Data Source:  BioPlex,STRINGDB
TUBA1A
Tchem
Novelty:  0.01030145
p_int:  0.999987147
p_ni:  0.000012853
Score:  0.795
Data Source:  BioPlex,STRINGDB
TUBA4A
Tchem
Novelty:  0.00820546
p_int:  0.999952415
p_ni:  0.000047585
Score:  0.645
Data Source:  BioPlex,STRINGDB
TUBA1C
Tchem
Novelty:  0.02804632
p_int:  0.999914636
p_ni:  0.000085364
Score:  0.899
Data Source:  BioPlex,STRINGDB
TUBA3E
Tchem
Novelty:  1.70475533
p_int:  0.999782497
p_ni:  0.000189347
p_wrong:  0.000028157
Score:  0.625
Data Source:  BioPlex,STRINGDB
TUBAL3
Tdark
Novelty:  1.0330894
p_int:  0.999496727
p_ni:  0.000210579
p_wrong:  0.000292694
Score:  0.165
Data Source:  BioPlex,STRINGDB
TTC5
Tbio
Novelty:  0.12127698
p_int:  0.991445187
p_ni:  0.000660761
p_wrong:  0.007894051
Score:  0.826
Data Source:  BioPlex,STRINGDB
ACTA2
Tbio
Novelty:  0.00199354
p_int:  0.965423005
p_ni:  0.034576995
Data Source:  BioPlex
NR1D1
Tchem
Family:  NR
Novelty:  0.00250799
Score:  0.814
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
basophil percentage of leukocytes
1
1
1
46.9
basophil count
1
1
1
42.3
glioblastoma multiforme
1
1
0
1.2
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
basophil percentage of leukocytes
1
46.9
basophil count
1
42.3
glioblastoma multiforme
0
1.2
31.4
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
t-complex 11 like 2
VGNC:8577
452199
Macaque
t-complex 11 like 2
702578
Mouse
MGI:2444679
216198
Rat
RGD:1307494
314683
Dog
t-complex 11 like 2
VGNC:47210
474532
Species
Name
OMA
EggNOG
Inparanoid
Chimp
t-complex 11 like 2
Macaque
t-complex 11 like 2
Mouse
Rat
Dog
t-complex 11 like 2
Publication Statistics
PubMed Score 0.78
PubMed score by year
PubTator Score 0.08
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title