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Tdark
TCP10L2
T-complex protein 10A homolog 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366832
  • ENSP00000355797
  • ENSG00000166984
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.67
cell line
0.39
cellular component
0.33
disease
0.23
tissue sample
0.23


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.2   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 5   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.2   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 5   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (36)
TCP10
Tbio
Novelty:  0.06680788
p_int:  1
Score:  0.71
Data Source:  BioPlex,STRINGDB
GRIPAP1
Tbio
Novelty:  0.09814766
p_int:  0.999998786
p_ni:  0.000001214
Score:  0.826
Data Source:  BioPlex,STRINGDB
TMF1
Tbio
Novelty:  0.02543575
p_int:  0.999987008
p_ni:  0.000012989
p_wrong:  3e-9
Score:  0.313
Data Source:  BioPlex,STRINGDB
MPRIP
Tbio
Family:  Enzyme
Novelty:  0.03253403
p_int:  0.995591224
p_ni:  0.00440877
p_wrong:  6e-9
Score:  0.211
Data Source:  BioPlex,STRINGDB
TCP10L
Tbio
Novelty:  0.24089479
p_int:  0.992426178
p_ni:  0.000192458
p_wrong:  0.007381365
Score:  0.351
Data Source:  BioPlex,STRINGDB
SASS6
Tbio
Novelty:  0.00680548
Score:  0.816
Data Source:  STRINGDB
STIL
Tbio
Novelty:  0.01053211
Score:  0.752
Data Source:  STRINGDB
GABPB1
Tbio
Novelty:  0.01518726
Score:  0.716
Data Source:  STRINGDB
GABPB2
Tbio
Novelty:  0.52630478
Score:  0.716
Data Source:  STRINGDB
ERMARD
Tdark
Novelty:  0.3424066
Score:  0.69
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
9
5
5
1.2
98.9
serum non-albumin protein measurement
2
2
2
72.9
keratinocyte carcinoma
1
1
0
1.1
68.5
primary biliary cirrhosis
2
2
2
60.2
triglyceride measurement
1
1
0
1.5
49.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
5
1.2
98.9
serum non-albumin protein measurement
2
72.9
keratinocyte carcinoma
0
1.1
68.5
primary biliary cirrhosis
2
60.2
triglyceride measurement
0
1.5
49.9
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.20
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title