Tbio TCP10L T-complex protein 10A homolog 1

Protein Summary

Description

May be involved in transcriptional regulation. Has in vitro transcription inhibition activity. Acts as a tumor suppressor in hepatocellular carcinoma (HCC) cells.

Uniprot Accession IDs

• Q8TDR4
• Q53EW0
• Q96LN5
• T-complex protein 10A-1

Gene Name

• TCP10L

Ensembl ID

• ENST00000300258
• ENSP00000300258
• ENSG00000242220

Symbol

• PRED77
• C21orf77
• TCP10A-1
• TCP10A-2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.61
microRNA	0.59
cell type or tissue	0.53
molecular function	0.53
biological process	0.52

Protein Classes

PANTHER Classes

Protein / Transferase / T-complex Protein 10a Homolog 1

Protein / Receptor / T-complex Protein 10a Homolog 1

DTO Classes

Protein / Enzyme / Transferase / T-complex Protein 10a Homolog 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.8   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 62   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.8   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0