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Tdark
TCEANC2
Transcription elongation factor A N-terminal and central domain-containing protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000234827
  • ENSP00000234827
  • ENSG00000116205
  • ENST00000648983
  • ENSP00000498109

Symbol
  • C1orf83
  • C1orf83
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.76
microRNA
0.76
histone modification site profile
0.75
transcription factor binding site profile
0.64
tissue sample
0.62


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.74   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 108   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.74   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 108   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (72)
UBE2R2
Tbio
Novelty:  0.29593236
p_int:  0.999996575
p_ni:  0.000003374
p_wrong:  5.2e-8
Score:  0.28
Data Source:  BioPlex,STRINGDB
WDR70
Tdark
Novelty:  0.37521871
p_int:  0.999981995
p_ni:  0.000018
p_wrong:  5e-9
Score:  0.207
Data Source:  BioPlex,STRINGDB
UBXN7
Tbio
Novelty:  0.07437638
p_int:  0.999978276
p_ni:  0.000021724
p_wrong:  1e-9
Score:  0.691
Data Source:  BioPlex,STRINGDB
CDC34
Tbio
Novelty:  0.00650407
p_int:  0.999967589
p_ni:  0.00003241
p_wrong:  1e-9
Score:  0.237
Data Source:  BioPlex,STRINGDB
ANKHD1
Tbio
Novelty:  0.05390096
p_int:  0.999929746
p_ni:  0.000070254
Data Source:  BioPlex
DCAF16
Tdark
Novelty:  0.35666992
p_int:  0.999416321
p_ni:  0.000565437
p_wrong:  0.000018242
Data Source:  BioPlex
ARIH1
Tbio
Family:  Enzyme
Novelty:  0.0258739
p_int:  0.998954597
p_ni:  0.001045403
Data Source:  BioPlex
SLC4A1AP
Tdark
Family:  Transporter
Novelty:  0.41125302
p_int:  0.998675332
p_ni:  0.001324668
Score:  0.181
Data Source:  BioPlex,STRINGDB
PHKA2
Tbio
Family:  Kinase
Novelty:  0.00461145
p_int:  0.998286037
p_ni:  0.001700811
p_wrong:  0.000013152
Score:  0.734
Data Source:  BioPlex,STRINGDB
RAD18
Tbio
Family:  Enzyme
Novelty:  0.00519213
p_int:  0.996142449
p_ni:  0.003857551
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
1
62.8
heel bone mineral density
1
1
1
50.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
62.8
heel bone mineral density
1
50.9
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1913776
66526
Rat
RGD:1359481
366431
Dog
transcription elongation factor A N-terminal and central domain containing 2
VGNC:53456
610613
Horse
transcription elongation factor A N-terminal and central domain containing 2
VGNC:50774
100060596
Cow
transcription elongation factor A N-terminal and central domain containing 2
539385
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
transcription elongation factor A N-terminal and central domain containing 2
Horse
transcription elongation factor A N-terminal and central domain containing 2
Cow
transcription elongation factor A N-terminal and central domain containing 2
Publication Statistics
PubMed Score 2.74
PubMed score by year
PubTator Score 1.60
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title