TBC1D2B
TBC1 domain family member 2B
Protein Summary
May act as a GTPase-activating protein.
- ENST00000300584
- ENSP00000300584
- ENSG00000167202
- ENST00000409931
- ENSP00000387165
- KIAA1055
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
interacting protein | 0.81 | ||
cell line | 0.6 | ||
tissue sample | 0.59 | ||
disease perturbation | 0.56 | ||
microRNA | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.56 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 33 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.56 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 33 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (64)
CEP120
Novelty: 0.07215656
p_int: 0.999996668
p_ni: 0.000002783
p_wrong: 5.48e-7
Data Source: BioPlex
PAK5
Family: Kinase
Novelty: 0.02138632
p_int: 0.99997462
p_ni: 0.00002538
Score: 0.206
Data Source: BioPlex,STRINGDB
ALOX5
Family: Enzyme
Novelty: 0.00062988
p_int: 0.999942066
p_ni: 0.000057934
Data Source: BioPlex
PSMC3
Family: Enzyme
Novelty: 0.04026019
p_int: 0.995515944
p_ni: 0.004484056
Score: 0.152
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (5)
Functions (2)
Components (1)
Processes (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations (null)
GWAS Traits (4)
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
serum albumin measurement | 1 | 3 | 3 | 80.5 | |||||
hematocrit | 1 | 1 | 1 | 10.2 | |||||
hemoglobin measurement | 1 | 1 | 1 | 9.8 | |||||
cigarettes per day measurement | 1 | 1 | 1 | 4.1 | |||||
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
serum albumin measurement | 3 | 80.5 | |||||
hematocrit | 1 | 10.2 | |||||
hemoglobin measurement | 1 | 9.8 | |||||
cigarettes per day measurement | 1 | 4.1 | |||||
Find similar targets by:
IDG Resources
Orthologs (14)
1 – 5 of 14
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | TBC1 domain family member 2B | VGNC:3523 | 453563 | |||||
Macaque | TBC1 domain family member 2B | 716076 | ||||||
Mouse | MGI:1914266 | 67016 | ||||||
Rat | RGD:1307436 | 315880 | ||||||
Dog | TBC1 domain family member 2B | VGNC:47145 | 488776 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | TBC1 domain family member 2B | |||||
Macaque | TBC1 domain family member 2B | |||||
Mouse | ||||||
Rat | ||||||
Dog | TBC1 domain family member 2B | |||||
Publication Statistics
PubMed Score 1.56
PubMed score by year
PubTator Score 0.41
PubTator score by year
Related Publications
Text Mined References (8)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
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