You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
TANC2
Protein TANC2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000389520
  • ENSP00000374171
  • ENSG00000170921
  • ENST00000424789
  • ENSP00000387593

Symbol
  • KIAA1148
  • KIAA1636
  • rols
  • ROLSA
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
1
transcription factor perturbation
0.88
protein domain
0.85
interacting protein
0.74
virus perturbation
0.72


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.75   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 13   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.75   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 13   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (33)
PPP1CA
Tchem
Family:  Enzyme
Novelty:  0.00354658
p_int:  0.999999956
p_ni:  2.9e-8
p_wrong:  1.5e-8
Score:  0.607
Data Source:  BioPlex,STRINGDB
PPP1CC
Tchem
Family:  Enzyme
Novelty:  0.00465946
p_int:  0.999999941
p_ni:  4.2e-8
p_wrong:  1.7e-8
Score:  0.608
Data Source:  BioPlex,STRINGDB
TAX1BP3
Tbio
Novelty:  0.01605171
p_int:  0.999999813
p_ni:  1.86e-7
Data Source:  BioPlex
ZYX
Tbio
Novelty:  0.00375452
p_int:  0.99999284
p_ni:  0.00000716
Score:  0.369
Data Source:  BioPlex,STRINGDB
PAK5
Tchem
Family:  Kinase
Novelty:  0.02138632
p_int:  0.999971845
p_ni:  0.000028155
Score:  0.284
Data Source:  BioPlex,STRINGDB
FJX1
Tbio
Novelty:  0.07957088
Score:  0.707
Data Source:  STRINGDB
ZFAND5
Tbio
Novelty:  0.09728886
Score:  0.668
Data Source:  STRINGDB
CHKA
Tchem
Family:  Kinase
Novelty:  0.00237839
Score:  0.653
Data Source:  STRINGDB
DLG5
Tbio
Novelty:  0.01630244
Score:  0.634
Data Source:  STRINGDB
TRMT13
Tdark
Novelty:  3.91234304
Score:  0.597
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (24)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood metabolite measurement
2
3
6
94.2
serum metabolite measurement
2
3
8
90.9
angiotensin converting enzyme activity measurement
1
1
0
16.2
77
2
2
2
76.7
diastolic blood pressure
3
3
2
2.1
73.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood metabolite measurement
6
94.2
serum metabolite measurement
8
90.9
angiotensin converting enzyme activity measurement
0
16.2
77
2
76.7
diastolic blood pressure
2
2.1
73.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
VGNC:9674
454784
Mouse
MGI:2444121
77097
Rat
RGD:1309285
303599
Dog
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
VGNC:47099
480483
Horse
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
VGNC:23865
100054415
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Mouse
Rat
Dog
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Horse
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Publication Statistics
PubMed Score 12.75
PubMed score by year
PubTator Score 7.42
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title