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Tbio
SYPL1
Synaptophysin-like protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000011473
  • ENSP00000011473
  • ENSG00000008282
  • ENST00000455385
  • ENSP00000388336

Symbol
  • SYPL
  • SYPL
  • H-SP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
1
co-expressed gene
0.89
transcription factor perturbation
0.88
transcription factor binding site profile
0.86
transcription factor
0.83


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.22   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 154   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.22   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 154   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (19)
VAMP8
Tbio
Novelty:  0.01083228
p_int:  0.999993692
p_ni:  0.000001971
p_wrong:  0.000004338
Score:  0.309
Data Source:  BioPlex,STRINGDB
VAMP3
Tbio
Novelty:  0.00694332
p_int:  0.99993168
p_ni:  0.000068296
p_wrong:  2.3e-8
Score:  0.449
Data Source:  BioPlex,STRINGDB
VAMP2
Tbio
Novelty:  0.00187736
p_int:  0.999758124
p_ni:  0.000241876
Score:  0.54
Data Source:  BioPlex,STRINGDB
LGALS3
Tchem
Novelty:  0.00032754
p_int:  0.86749192
p_ni:  0.13250808
Data Source:  BioPlex
ZNF550
Tdark
Family:  TF
Novelty:  18
Score:  0.743
Data Source:  STRINGDB
SCAMP1
Tbio
Novelty:  0.03293648
Score:  0.724
Data Source:  STRINGDB
CDHR3
Tbio
Novelty:  0.02504301
Score:  0.588
Data Source:  STRINGDB
NAPG
Tbio
Novelty:  0.02295985
Score:  0.587
Data Source:  STRINGDB
MAGT1
Tbio
Novelty:  0.02144318
Score:  0.555
Data Source:  STRINGDB
STXBP3
Tbio
Novelty:  0.03346737
Score:  0.553
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (7)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Traceable Author Statement (TAS)
ProtInc
Traceable Author Statement (TAS)
ProtInc
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
Ensembl
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
childhood onset asthma
1
1
0
1.3
61
susceptibility to childhood ear infection measurement
1
1
0
1.1
29
C-reactive protein measurement
1
1
1
28.1
1
1
0
1.1
21.5
1
1
0
1.1
5.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
childhood onset asthma
0
1.3
61
susceptibility to childhood ear infection measurement
0
1.1
29
C-reactive protein measurement
1
28.1
0
1.1
21.5
0
1.1
5.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
synaptophysin like 1
VGNC:8766
463647
Macaque
synaptophysin like 1
698350
Mouse
MGI:108081
19027
Rat
RGD:1359569
366595
Dog
synaptophysin like 1
VGNC:47039
475889
Species
Name
OMA
EggNOG
Inparanoid
Chimp
synaptophysin like 1
Macaque
synaptophysin like 1
Mouse
Rat
Dog
synaptophysin like 1
Publication Statistics
PubMed Score 24.22
PubMed score by year
PubTator Score 14.20
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title