SYPL1
Synaptophysin-like protein 1
Protein Summary
- ENST00000011473
- ENSP00000011473
- ENSG00000008282
- ENST00000455385
- ENSP00000388336
- SYPL
- SYPL
- H-SP1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 1 | ||
co-expressed gene | 0.89 | ||
transcription factor perturbation | 0.88 | ||
transcription factor binding site profile | 0.86 | ||
transcription factor | 0.83 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 24.22 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 154 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 24.22 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 154 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (19)
VAMP8
Novelty: 0.01083228
p_int: 0.999993692
p_ni: 0.000001971
p_wrong: 0.000004338
Score: 0.309
Data Source: BioPlex,STRINGDB
VAMP3
Novelty: 0.00694332
p_int: 0.99993168
p_ni: 0.000068296
p_wrong: 2.3e-8
Score: 0.449
Data Source: BioPlex,STRINGDB
VAMP2
Novelty: 0.00187736
p_int: 0.999758124
p_ni: 0.000241876
Score: 0.54
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (7)
Components (6)
Processes (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-SubCell | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Disease Associations ()
GWAS Traits (5)
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
childhood onset asthma | 1 | 1 | 0 | 1.3 | 61 | ||||
susceptibility to childhood ear infection measurement | 1 | 1 | 0 | 1.1 | 29 | ||||
C-reactive protein measurement | 1 | 1 | 1 | 28.1 | |||||
1 | 1 | 0 | 1.1 | 21.5 | |||||
1 | 1 | 0 | 1.1 | 5.5 | |||||
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
childhood onset asthma | 0 | 1.3 | 61 | ||||
susceptibility to childhood ear infection measurement | 0 | 1.1 | 29 | ||||
C-reactive protein measurement | 1 | 28.1 | |||||
0 | 1.1 | 21.5 | |||||
0 | 1.1 | 5.5 | |||||
Find similar targets by:
IDG Resources
Orthologs (15)
1 – 5 of 15
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | synaptophysin like 1 | VGNC:8766 | 463647 | |||||
Macaque | synaptophysin like 1 | 698350 | ||||||
Mouse | MGI:108081 | 19027 | ||||||
Rat | RGD:1359569 | 366595 | ||||||
Dog | synaptophysin like 1 | VGNC:47039 | 475889 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | synaptophysin like 1 | |||||
Macaque | synaptophysin like 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | synaptophysin like 1 | |||||
Publication Statistics
PubMed Score 24.22
PubMed score by year
PubTator Score 14.20
PubTator score by year
Related Publications
Text Mined References (18)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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