You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
SYNJ2BP
Synaptojanin-2-binding protein

Protein Summary
Description
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000256366
  • ENSP00000256366
  • ENSG00000213463

Symbol
  • OMP25
  • ARIP2
  • OMP25
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.97
interacting protein
0.95
kinase perturbation
0.93
transcription factor perturbation
0.91
histone modification site profile
0.81


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 86.32   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 103   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 86.32   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 103   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 17
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0