Tdark SVOPL Putative transporter SVOPL

Protein Summary

Description

The protein encoded by this gene is thought to be a member of solute carrier family 22, which includes transmembrane proteins that transport toxins and drugs from the body. This gene is a paralog of the SVOP gene that encodes synaptic vesicle 2-related protein. [provided by RefSeq, Sep 2016]

Uniprot Accession IDs

• Q8N434

Gene Name

• SVOPL

Ensembl ID

• ENST00000288513
• ENSP00000288513
• ENSG00000157703
• ENST00000419765
• ENSP00000405482
• ENST00000436657
• ENSP00000417018

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.99
virus perturbation	0.64
tissue sample	0.61
cell line	0.55
cell type or tissue	0.49

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.91   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 87   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.91   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0