You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
SUSD5
Sushi domain-containing protein 5

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000309558
  • ENSP00000308727
  • ENSG00000173705

Symbol
  • KIAA0527
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.83
phenotype
0.63
kinase perturbation
0.6
protein domain
0.58
microRNA
0.53


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.78   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 84   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.78   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 84   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
FCN1
Tbio
Novelty:  0.01037775
p_int:  0.999999125
p_ni:  8.72e-7
p_wrong:  2e-9
Score:  0.209
Data Source:  BioPlex,STRINGDB
DEFA5
Tbio
Novelty:  0.00863727
p_int:  0.999993115
p_ni:  0.000006885
Data Source:  BioPlex
SERPINA12
Tbio
Novelty:  0.00549132
p_int:  0.999986778
p_ni:  0.000005254
p_wrong:  0.000007967
Data Source:  BioPlex
CSTL1
Tbio
Novelty:  0.13370814
p_int:  0.999912762
p_ni:  0.000002801
p_wrong:  0.000084436
Data Source:  BioPlex
LGALS8
Tchem
Novelty:  0.00623836
p_int:  0.999906276
p_ni:  0.000093716
p_wrong:  8e-9
Data Source:  BioPlex
FAM19A4
Tbio
Novelty:  0.04305684
p_int:  0.999904712
p_ni:  0.000095285
p_wrong:  2e-9
Data Source:  BioPlex
AMZ1
Tdark
Family:  Enzyme
Novelty:  0.246305
p_int:  0.999893703
p_ni:  0.000106282
p_wrong:  1.5e-8
Score:  0.189
Data Source:  BioPlex,STRINGDB
IGFBP1
Tchem
Novelty:  0.0006975
p_int:  0.999491741
p_ni:  0.000507674
p_wrong:  5.85e-7
Score:  0.177
Data Source:  BioPlex,STRINGDB
CD1E
Tbio
Novelty:  0.00171622
p_int:  0.999333424
p_ni:  0.000664679
p_wrong:  0.000001897
Data Source:  BioPlex
NRIP2
Tdark
Novelty:  0.5598619
Score:  0.697
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
1
1
1
77.9
aspartate aminotransferase measurement
1
1
0
6.8
51.7
1
1
1
21.5
BMI-adjusted hip circumference
1
1
1
17.8
heel bone mineral density
2
1
2
12.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
1
77.9
aspartate aminotransferase measurement
0
6.8
51.7
1
21.5
BMI-adjusted hip circumference
1
17.8
heel bone mineral density
2
12.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
sushi domain containing 5
VGNC:2596
470782
Macaque
sushi domain containing 5
709616
Mouse
MGI:2685972
382111
Rat
RGD:1561132
301039
Dog
sushi domain containing 5
VGNC:52905
485576
Species
Name
OMA
EggNOG
Inparanoid
Chimp
sushi domain containing 5
Macaque
sushi domain containing 5
Mouse
Rat
Dog
sushi domain containing 5
Publication Statistics
PubMed Score 0.78
PubMed score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title