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Tdark
SUSD1
Sushi domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374264
  • ENSP00000363382
  • ENSG00000106868
  • ENST00000374270
  • ENSP00000363388
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.97
histone modification site profile
0.79
cell type or tissue
0.65
tissue sample
0.63
gene perturbation
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.58   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 16   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.58   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 16   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (39)
DEFA1
Tbio
Novelty:  0.01027492
p_int:  0.999829033
p_ni:  0.000170955
p_wrong:  1.2e-8
Data Source:  BioPlex
G0S2
Tbio
Novelty:  0.02273959
p_int:  0.999609046
p_ni:  0.000354934
p_wrong:  0.00003602
Data Source:  BioPlex
PATE1
Tbio
Novelty:  0.0705075
p_int:  0.999548226
p_ni:  0.000451645
p_wrong:  1.29e-7
Data Source:  BioPlex
ST8SIA4
Tbio
Family:  Enzyme
Novelty:  0.00338436
p_int:  0.999466985
p_ni:  0.000533015
Data Source:  BioPlex
PSCA
Tbio
Novelty:  0.00323778
p_int:  0.999345552
p_ni:  0.000654412
p_wrong:  3.6e-8
Data Source:  BioPlex
B4GAT1
Tbio
Family:  Enzyme
Novelty:  0.14959923
p_int:  0.998685955
p_ni:  0.001313918
p_wrong:  1.26e-7
Score:  0.19
Data Source:  BioPlex,STRINGDB
PTPRK
Tbio
Family:  Enzyme
Novelty:  0.03149943
p_int:  0.998359209
p_ni:  0.001640754
p_wrong:  3.7e-8
Data Source:  BioPlex
LMAN2L
Tbio
Novelty:  0.04364985
p_int:  0.998169753
p_ni:  0.001730518
p_wrong:  0.000099728
Data Source:  BioPlex
CLEC2D
Tbio
Novelty:  0.02501194
p_int:  0.998069
p_ni:  0.001930994
p_wrong:  6e-9
Data Source:  BioPlex
SCGB1D1
Tbio
Novelty:  0.04199997
p_int:  0.997396725
p_ni:  0.002603267
p_wrong:  7e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
2
3
3
85.8
testosterone measurement
2
1
2
81.3
hematocrit
2
3
3
80.2
reticulocyte count
1
2
2
63
red blood cell distribution width
1
1
1
62.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
3
85.8
testosterone measurement
2
81.3
hematocrit
3
80.2
reticulocyte count
2
63
red blood cell distribution width
1
62.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
sushi domain containing 1
707656
Mouse
MGI:3651543
634731
Dog
sushi domain containing 1
VGNC:46997
481667
Horse
sushi domain containing 1
VGNC:23771
100057493
Cow
sushi domain containing 1
VGNC:35486
518850
Species
Name
OMA
EggNOG
Inparanoid
Macaque
sushi domain containing 1
Mouse
Dog
sushi domain containing 1
Horse
sushi domain containing 1
Cow
sushi domain containing 1
Publication Statistics
PubMed Score 1.58
PubMed score by year
PubTator Score 0.39
PubTator score by year
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Related Publications
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PMID
Year
Title