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Tdark
SUGP2
SURP and G-patch domain-containing protein 2

Protein Summary
Description
May play a role in mRNA splicing. This gene encodes a member of the arginine/serine-rich family of splicing factors. The encoded protein functions in mRNA processing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000330854
  • ENSP00000332373
  • ENSG00000064607
  • ENST00000337018
  • ENSP00000337926
  • ENST00000452918
  • ENSP00000389380
  • ENST00000594773
  • ENSP00000470915
  • ENST00000601879
  • ENSP00000472286

Symbol
  • KIAA0365
  • SFRS14
  • SFRS14
  • SRFS14
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.94
virus perturbation
0.94
disease perturbation
0.9
histone modification site profile
0.9
kinase perturbation
0.88


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.71   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 137   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.71   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 137   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (47)
RAB3IL1
Tbio
Novelty:  0.0167537
p_int:  0.996472655
p_ni:  0.003527345
Score:  0.228
Data Source:  BioPlex,STRINGDB
ELAVL2
Tbio
Novelty:  0.00370708
p_int:  0.985165442
p_ni:  0.014834558
Data Source:  BioPlex
CLEC11A
Tbio
Novelty:  0.03060601
p_int:  0.943963688
p_ni:  0.056036312
Score:  0.193
Data Source:  BioPlex,STRINGDB
NXF2
Tbio
Novelty:  0.04733504
p_int:  0.890221307
p_ni:  0.109778693
Data Source:  BioPlex
NUP62CL
Tdark
Novelty:  2.93223607
p_int:  0.797361158
p_ni:  0.202638842
Data Source:  BioPlex
MAP7
Tbio
Novelty:  0.01976296
p_int:  0.795683442
p_ni:  0.204316558
Data Source:  BioPlex
TMEM126B
Tbio
Novelty:  0.21278172
Score:  0.809
Data Source:  STRINGDB
C7orf25
Tdark
Novelty:  3.59798701
Score:  0.771
Data Source:  STRINGDB
PIGO
Tbio
Family:  Enzyme
Novelty:  0.05949164
Score:  0.724
Data Source:  STRINGDB
FEM1C
Tbio
Novelty:  0.09385738
Score:  0.723
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
1
2
2
88.3
low density lipoprotein cholesterol measurement
1
2
2
87.4
apolipoprotein B measurement
1
2
2
85.4
triglyceride measurement
1
2
2
83.7
bilirubin measurement
1
1
1
61.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
2
88.3
low density lipoprotein cholesterol measurement
2
87.4
apolipoprotein B measurement
2
85.4
triglyceride measurement
2
83.7
bilirubin measurement
1
61.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SURP and G-patch domain containing 2
VGNC:13519
468774
Macaque
SURP and G-patch domain containing 2
719666
Mouse
MGI:2678085
234373
Rat
RGD:1306042
361126
Dog
SURP and G-patch domain containing 2
VGNC:46973
487882
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SURP and G-patch domain containing 2
Macaque
SURP and G-patch domain containing 2
Mouse
Rat
Dog
SURP and G-patch domain containing 2
Publication Statistics
PubMed Score 1.71
PubMed score by year
PubTator Score 0.86
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title