Tbio SUGP1 SURP and G-patch domain-containing protein 1

Protein Summary

Description

Plays a role in pre-mRNA splicing. SF4 is a member of the SURP family of splicing factors.[supplied by OMIM, Sep 2003]

Uniprot Accession IDs

• Q8IWZ8
• O60378
• Q6P3X9
• Q8TCQ4
• Q8WWT4
• Q8WWT5
• Q9NTG3

Gene Name

• SUGP1

Ensembl ID

• ENST00000247001
• ENSP00000247001
• ENSG00000105705
• ENST00000588731
• ENSP00000465413

Symbol

• SF4
• RBP
• SF4
• F23858

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.91
histone modification site profile	0.89
trait	0.75
transcription factor binding site profile	0.73
tissue sample	0.68

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Mrna Processing Factor / Mrna Splicing Factor / Surp And G-patch Domain-containing Protein 1

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Mrna Processing Factor / Mrna Splicing Factor / Surp And G-patch Domain-containing Protein 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 318.75   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 145   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 318.75   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 145   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0