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Tbio
STXBP6
Syntaxin-binding protein 6

Protein Summary
Description
Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis. STXBP6 binds components of the SNARE complex (see MIM 603215) and may be involved in regulating SNARE complex formation (Scales et al., 2002 [PubMed 12145319]).[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000323944
  • ENSP00000324302
  • ENSG00000168952
  • ENST00000396700
  • ENSP00000379928
  • ENST00000419632
  • ENSP00000397212
  • ENST00000546511
  • ENSP00000449536
  • ENST00000548369
  • ENSP00000447655
  • ENST00000550887
  • ENSP00000449379

Symbol
  • amisyn
  • HSPC156
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.76
trait
0.75
histone modification site profile
0.73
transcription factor
0.69
disease
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.37   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 208   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.37   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 208   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0