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Tbio
STXBP3
Syntaxin-binding protein 3

Protein Summary
Description
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000370008
  • ENSP00000359025
  • ENSG00000116266

Symbol
  • PSP
  • MUNC18C
  • UNC-18C
  • MUNC18-3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.96
biological process
0.77
transcription factor binding site profile
0.74
virus perturbation
0.72
histone modification site profile
0.66


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.64   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 208   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.64   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 208   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0