Protein Summary
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. This gene belongs to the syntaxin family and encodes a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE). The encoded protein is involved in docking and fusion events at the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
- ENST00000343587
- ENSP00000339350
- ENSG00000104915
- ENST00000587230
- ENSP00000466298
- SYN10
- SYN10
- hsyn10
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.73 | ||
cellular component | 0.64 | ||
tissue sample | 0.59 | ||
protein domain | 0.58 | ||
transcription factor binding site profile | 0.58 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 13.52 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 138 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 13.52 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 138 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 9
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (105)
STX12
Novelty: 0.03836262
p_int: 0.999885661
p_ni: 0.000114339
p_wrong: 1e-9
Score: 0.973
Data Source: BioPlex,STRINGDB
VAMP5
Novelty: 0.09958312
p_int: 0.999731934
p_ni: 0.000268063
p_wrong: 3e-9
Score: 0.762
Data Source: BioPlex,STRINGDB
VAMP4
Novelty: 0.02949854
p_int: 0.999082921
p_ni: 0.000917074
p_wrong: 4e-9
Score: 0.997
Data Source: BioPlex,STRINGDB
STX7
Novelty: 0.03109969
p_int: 0.99802474
p_ni: 0.001952561
p_wrong: 0.000022699
Score: 0.935
Data Source: BioPlex,STRINGDB
TMEM200A
Novelty: 0.25580793
p_int: 0.998010422
p_ni: 0.001901617
p_wrong: 0.000087961
Score: 0.638
Data Source: BioPlex,STRINGDB
KIR2DL1
Novelty: 0.00523657
p_int: 0.997729358
p_ni: 0.002270172
p_wrong: 4.7e-7
Data Source: BioPlex
CLEC12A
Novelty: 0.01478908
p_int: 0.996541019
p_ni: 0.00345887
p_wrong: 1.11e-7
Score: 0.671
Data Source: BioPlex,STRINGDB
STX11
Novelty: 0.01670743
p_int: 0.994019884
p_ni: 0.005980064
p_wrong: 5.2e-8
Score: 0.816
Data Source: BioPlex,STRINGDB
LRRIQ1
Novelty: 1.8251367
p_int: 0.967088187
p_ni: 0.032904463
p_wrong: 0.00000735
Data Source: BioPlex
LPAR6
Family: GPCR
Novelty: 0.01801122
p_int: 0.942707654
p_ni: 0.057221856
p_wrong: 0.00007049
Data Source: BioPlex
Nearest Tclin Targets
Pathways (6)
Reactome (4)
KEGG (1)
PathwayCommons (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Intra-Golgi and retrograde Golgi-to-ER traffic | ||||
Reactome | Membrane Trafficking | ||||
Reactome | Retrograde transport at the Trans-Golgi-Network | ||||
Reactome | Vesicle-mediated transport | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Intra-Golgi and retrograde Golgi-to-ER traffic | ||||
Membrane Trafficking | ||||
Retrograde transport at the Trans-Golgi-Network | ||||
Vesicle-mediated transport | ||||
Viral Interactions (0)
Gene Ontology Terms (19)
Functions (3)
Components (10)
Processes (6)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations ()
GWAS Traits (20)
Items per page:
1 – 5 of 20
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
monocyte percentage of leukocytes | 2 | 4 | 4 | 88.4 | |||||
monocyte count | 2 | 2 | 2 | 86.8 | |||||
platelet crit | 1 | 2 | 2 | 77.6 | |||||
mean platelet volume | 2 | 2 | 2 | 76.2 | |||||
self reported educational attainment | 3 | 3 | 3 | 5.9 | 74.6 | ||||
Items per page:
1 – 5 of 20
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
monocyte percentage of leukocytes | 4 | 88.4 | |||||
monocyte count | 2 | 86.8 | |||||
platelet crit | 2 | 77.6 | |||||
mean platelet volume | 2 | 76.2 | |||||
self reported educational attainment | 3 | 5.9 | 74.6 | ||||
Find similar targets by:
IDG Resources
Orthologs (6)
1 – 5 of 6
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | syntaxin 10 | VGNC:2242 | 455760 | |||||
Macaque | syntaxin 10 | 717208 | ||||||
Dog | syntaxin 10 | VGNC:46949 | 476691 | |||||
Cow | syntaxin 10 | VGNC:35430 | 525379 | |||||
Pig | syntaxin 10 | 100627609 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | syntaxin 10 | |||||
Macaque | syntaxin 10 | |||||
Dog | syntaxin 10 | |||||
Cow | syntaxin 10 | |||||
Pig | syntaxin 10 | |||||
Publication Statistics
PubMed Score 13.52
PubMed score by year
PubTator Score 7.37
PubTator score by year
Related Publications
Text Mined References (10)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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