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Tbio
STRN4
Striatin-4

Protein Summary
Description
Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263280
  • ENSP00000263280
  • ENSG00000090372
  • ENST00000391910
  • ENSP00000375777
  • ENST00000435164
  • ENSP00000473607

Symbol
  • ZIN
  • ZIN
  • PPP2R6C
  • zinedin
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
hub protein
0.79
cell type or tissue
0.74
disease perturbation
0.68
tissue
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.01   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 162   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.01   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 162   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (78)
STRN
Tbio
Novelty:  0.01025814
p_int:  0.999999441
p_ni:  5.59e-7
Score:  0.87
Data Source:  BioPlex,STRINGDB
STRN3
Tbio
Novelty:  0.10331283
p_int:  0.999998256
p_ni:  0.000001744
Score:  0.871
Data Source:  BioPlex,STRINGDB
TRAF3IP3
Tbio
Novelty:  0.12180834
p_int:  0.999997023
p_ni:  0.000002977
Score:  0.862
Data Source:  BioPlex,STRINGDB
PPP2CB
Tbio
Family:  Enzyme
Novelty:  0.0483178
p_int:  0.999981991
p_ni:  0.000018009
Score:  0.929
Data Source:  BioPlex,STRINGDB
PPP2R1A
Tbio
Family:  Enzyme
Novelty:  0.01134139
p_int:  0.999914401
p_ni:  0.000085599
Score:  0.919
Data Source:  BioPlex,STRINGDB
STRIP2
Tbio
Novelty:  0.19321125
p_int:  0.999894073
p_ni:  0.000105927
Score:  0.798
Data Source:  BioPlex,STRINGDB
GEMIN2
Tbio
Novelty:  0.02072868
p_int:  0.99989365
p_ni:  0.00010635
Data Source:  BioPlex
PRDM14
Tbio
Family:  TF; Epigenetic
Novelty:  0.01776592
p_int:  0.999227649
p_ni:  0.000772351
Data Source:  BioPlex
TPTE2
Tbio
Family:  Enzyme
Novelty:  0.04710658
p_int:  0.996999834
p_ni:  0.003000166
Score:  0.163
Data Source:  BioPlex,STRINGDB
SNAP29
Tbio
Novelty:  0.02009206
p_int:  0.995581306
p_ni:  0.004418693
p_wrong:  1e-9
Score:  0.166
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
1
2
62.1
2
2
0
1.2
60.8
2
1
0
1.3
54.4
2
2
0
1.3
43.9
eosinophil count
1
1
1
40.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
62.1
0
1.2
60.8
0
1.3
54.4
0
1.3
43.9
eosinophil count
1
40.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
striatin 4
VGNC:3584
746354
Macaque
striatin 4
717661
Mouse
MGI:2142346
97387
Rat
RGD:1307030
308392
Dog
striatin 4
VGNC:46947
610799
Species
Name
OMA
EggNOG
Inparanoid
Chimp
striatin 4
Macaque
striatin 4
Mouse
Rat
Dog
striatin 4
Publication Statistics
PubMed Score 12.01
PubMed score by year
PubTator Score 27.23
PubTator score by year
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Related Publications
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PMID
Year
Title