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Tbio
STRN3
Striatin-3

Protein Summary
Description
Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355683
  • ENSP00000347909
  • ENSG00000196792
  • ENST00000357479
  • ENSP00000350071

Symbol
  • GS2NA
  • SG2NA
  • SG2NA
  • S/G2NA
  • PPP2R6B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
drug perturbation
0.96
kinase perturbation
0.88
protein domain
0.85
histone modification site profile
0.74
hub protein
0.71


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.21   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 119   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.21   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (84)
CTTNBP2NL
Tbio
Novelty:  0.52774527
p_int:  0.999999917
p_ni:  8.3e-8
Score:  0.942
Data Source:  BioPlex,STRINGDB
CTTNBP2
Tbio
Novelty:  0.00241
p_int:  0.999999806
p_ni:  1.94e-7
Score:  0.906
Data Source:  BioPlex,STRINGDB
MOB4
Tbio
Novelty:  0.03238981
p_int:  0.999999699
p_ni:  3.01e-7
Score:  0.96
Data Source:  BioPlex,STRINGDB
SLMAP
Tbio
Novelty:  0.03974856
p_int:  0.999998986
p_ni:  0.000001014
Score:  0.958
Data Source:  BioPlex,STRINGDB
TRAF3IP3
Tbio
Novelty:  0.12180834
p_int:  0.999998805
p_ni:  0.000001195
Score:  0.87
Data Source:  BioPlex,STRINGDB
STRN
Tbio
Novelty:  0.01025814
p_int:  0.999998505
p_ni:  0.000001495
Score:  0.865
Data Source:  BioPlex,STRINGDB
STRN4
Tbio
Novelty:  0.09936184
p_int:  0.999998256
p_ni:  0.000001744
Score:  0.871
Data Source:  BioPlex,STRINGDB
SIKE1
Tbio
Novelty:  0.14549184
p_int:  0.999997603
p_ni:  0.000002396
p_wrong:  2e-9
Score:  0.918
Data Source:  BioPlex,STRINGDB
STRIP1
Tbio
Novelty:  0.13320106
p_int:  0.999997257
p_ni:  0.000002743
Score:  0.963
Data Source:  BioPlex,STRINGDB
STRIP2
Tbio
Novelty:  0.19321125
p_int:  0.999983505
p_ni:  0.00001646
p_wrong:  3.5e-8
Score:  0.965
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (20)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
3
3
3
86.3
brain measurement
1
1
0
13.5
73.2
white matter microstructure measurement
2
2
2
72.4
cortical surface area measurement
1
1
0
9.3
63.4
cortical thickness
1
1
0
8.5
58.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
3
86.3
brain measurement
0
13.5
73.2
white matter microstructure measurement
2
72.4
cortical surface area measurement
0
9.3
63.4
cortical thickness
0
8.5
58.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
striatin 3
VGNC:6774
452838
Macaque
striatin 3
717081
Mouse
MGI:2151064
94186
Rat
RGD:621827
114520
Dog
striatin 3
VGNC:46946
480282
Species
Name
OMA
EggNOG
Inparanoid
Chimp
striatin 3
Macaque
striatin 3
Mouse
Rat
Dog
striatin 3
Publication Statistics
PubMed Score 14.21
PubMed score by year
PubTator Score 3.59
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title