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Tbio
STRIP2
Striatin-interacting protein 2

Protein Summary
Description
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000249344
  • ENSP00000249344
  • ENSG00000128578
  • ENST00000435494
  • ENSP00000392393

Symbol
  • FAM40B
  • KIAA1170
  • FAM40B
  • FAR11B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
transcription factor binding site profile
0.7
gene perturbation
0.68
microRNA
0.63
cell line
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.45   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 55   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.45   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 55   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (48)
TRAF3IP3
Tbio
Novelty:  0.12180834
p_int:  0.999999988
p_ni:  3e-9
p_wrong:  8e-9
Score:  0.86
Data Source:  BioPlex,STRINGDB
PPP2CB
Tbio
Family:  Enzyme
Novelty:  0.0483178
p_int:  0.999999938
p_ni:  4e-8
p_wrong:  2.2e-8
Score:  0.719
Data Source:  BioPlex,STRINGDB
STRIP1
Tbio
Novelty:  0.13320106
p_int:  0.99999974
p_ni:  2.6e-7
Score:  0.863
Data Source:  BioPlex,STRINGDB
CTTNBP2NL
Tbio
Novelty:  0.52774527
p_int:  0.999998591
p_ni:  0.000001409
Score:  0.958
Data Source:  BioPlex,STRINGDB
PRDM14
Tbio
Family:  TF; Epigenetic
Novelty:  0.01776592
p_int:  0.99999813
p_ni:  0.00000187
Score:  0.206
Data Source:  BioPlex,STRINGDB
STRN3
Tbio
Novelty:  0.10331283
p_int:  0.999983505
p_ni:  0.00001646
p_wrong:  3.5e-8
Score:  0.965
Data Source:  BioPlex,STRINGDB
CYTH2
Tbio
Novelty:  0.03560664
p_int:  0.99995925
p_ni:  0.00004075
Data Source:  BioPlex
SLMAP
Tbio
Novelty:  0.03974856
p_int:  0.999954543
p_ni:  0.000045457
Score:  0.829
Data Source:  BioPlex,STRINGDB
STRN4
Tbio
Novelty:  0.09936184
p_int:  0.999894073
p_ni:  0.000105927
Score:  0.798
Data Source:  BioPlex,STRINGDB
MON1B
Tbio
Novelty:  0.13486379
p_int:  0.999813409
p_ni:  0.000178526
p_wrong:  0.000008066
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
HPA
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
2
1
2
67.7
hematocrit
2
1
2
64.9
mean platelet volume
2
1
2
21.4
red blood cell distribution width
1
1
1
4.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
2
67.7
hematocrit
2
64.9
mean platelet volume
2
21.4
red blood cell distribution width
1
4.5
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
striatin interacting protein 2
VGNC:4524
463721
Macaque
striatin interacting protein 2
701573
Mouse
MGI:2444363
320609
Dog
striatin interacting protein 2
VGNC:46944
482261
Horse
striatin interacting protein 2
VGNC:23718
100071840
Species
Name
OMA
EggNOG
Inparanoid
Chimp
striatin interacting protein 2
Macaque
striatin interacting protein 2
Mouse
Dog
striatin interacting protein 2
Horse
striatin interacting protein 2
Publication Statistics
PubMed Score 7.45
PubMed score by year
PubTator Score 6.38
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title