STRIP1
Striatin-interacting protein 1
Protein Summary
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. This gene encodes a member of the striatin-interacting phosphatase and kinase complex, which is involved in localization of the Golgi body. The encoded protein participates in cytosketelal organization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
- ENST00000369795
- ENSP00000358810
- ENSG00000143093
- ENST00000369796
- ENSP00000358811
- ENST00000485775
- ENSP00000476025
- FAM40A
- KIAA1761
- FAM40A
- FAR11A
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
ligand (protein) perturbation | 0.83 | ||
histone modification site profile | 0.7 | ||
tissue | 0.61 | ||
transcription factor binding site profile | 0.59 | ||
cell line | 0.57 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.29 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 157 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.29 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 157 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (62)
TRAF3IP3
Novelty: 0.12180834
p_int: 0.999999848
p_ni: 1.52e-7
p_wrong: 1e-9
Score: 0.86
Data Source: BioPlex,STRINGDB
STRIP2
Novelty: 0.19321125
p_int: 0.99999974
p_ni: 2.6e-7
Score: 0.863
Data Source: BioPlex,STRINGDB
STRN
Novelty: 0.01025814
p_int: 0.999998297
p_ni: 0.000001703
Score: 0.976
Data Source: BioPlex,STRINGDB
STRN3
Novelty: 0.10331283
p_int: 0.999997257
p_ni: 0.000002743
Score: 0.963
Data Source: BioPlex,STRINGDB
PPP2CB
Family: Enzyme
Novelty: 0.0483178
p_int: 0.999993107
p_ni: 0.000006867
p_wrong: 2.6e-8
Score: 0.919
Data Source: BioPlex,STRINGDB
PRDM14
Family: TF; Epigenetic
Novelty: 0.01776592
p_int: 0.999947376
p_ni: 0.000052624
Data Source: BioPlex
PPP2R1A
Family: Enzyme
Novelty: 0.01134139
p_int: 0.999838509
p_ni: 0.000161491
Score: 0.948
Data Source: BioPlex,STRINGDB
STK25
Family: Kinase
Novelty: 0.03229688
p_int: 0.99885562
p_ni: 0.00114438
Score: 0.949
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (7)
Functions (2)
Components (3)
Processes (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Disease Associations (null)
GWAS Traits (12)
Items per page:
1 – 5 of 12
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
mathematical ability | 3 | 1 | 3 | 64.9 | |||||
self reported educational attainment | 1 | 1 | 1 | 62.1 | |||||
cognitive function measurement | 1 | 1 | 1 | 46.9 | |||||
bone density | 2 | 2 | 3 | 45.5 | |||||
age at first sexual intercourse measurement | 1 | 1 | 1 | 38.8 | |||||
Items per page:
1 – 5 of 12
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
mathematical ability | 3 | 64.9 | |||||
self reported educational attainment | 1 | 62.1 | |||||
cognitive function measurement | 1 | 46.9 | |||||
bone density | 3 | 45.5 | |||||
age at first sexual intercourse measurement | 1 | 38.8 | |||||
Find similar targets by:
IDG Resources
Orthologs (14)
1 – 5 of 14
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | striatin interacting protein 1 | VGNC:1649 | 469417 | |||||
Macaque | striatin interacting protein 1 | 700799 | ||||||
Mouse | MGI:2443884 | 229707 | ||||||
Rat | RGD:1564249 | 362012 | ||||||
Dog | striatin interacting protein 1 | VGNC:46943 | 490117 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | striatin interacting protein 1 | |||||
Macaque | striatin interacting protein 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | striatin interacting protein 1 | |||||
Publication Statistics
PubMed Score 8.29
PubMed score by year
PubTator Score 8.97
PubTator score by year
Related Publications
Text Mined References (21)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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