You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
STMN4
Stathmin-4

Protein Summary
Description
Exhibits microtubule-destabilizing activity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265770
  • ENSP00000265770
  • ENSG00000015592
  • ENST00000350889
  • ENSP00000342538
  • ENST00000519997
  • ENSP00000428474
  • ENST00000523048
  • ENSP00000428428

Symbol
  • RB3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.71
PubMedID
0.64
gene perturbation
0.53
disease perturbation
0.49
transcription factor
0.46


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.77   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 145   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.77   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 145   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (114)
C7orf43
Tdark
Novelty:  1.11975505
p_int:  0.999998081
p_ni:  0.000001919
Score:  0.816
Data Source:  BioPlex,STRINGDB
TRAPPC9
Tbio
Novelty:  0.02703008
p_int:  0.999967229
p_ni:  0.000032771
Score:  0.782
Data Source:  BioPlex,STRINGDB
TRAPPC6B
Tbio
Novelty:  0.15086531
p_int:  0.999950478
p_ni:  0.000049522
Score:  0.81
Data Source:  BioPlex,STRINGDB
TRAPPC10
Tbio
Novelty:  0.03433058
p_int:  0.999938244
p_ni:  0.000061756
Score:  0.741
Data Source:  BioPlex,STRINGDB
CHMP5
Tbio
Novelty:  0.03378716
p_int:  0.999731209
p_ni:  2.4e-7
p_wrong:  0.00026855
Score:  0.798
Data Source:  BioPlex,STRINGDB
TRAPPC4
Tbio
Novelty:  0.05749912
p_int:  0.999325478
p_ni:  0.00067452
p_wrong:  1e-9
Score:  0.742
Data Source:  BioPlex,STRINGDB
VTA1
Tbio
Novelty:  0.01697854
p_int:  0.998913667
p_ni:  0.001086333
Score:  0.558
Data Source:  BioPlex,STRINGDB
TRAPPC1
Tbio
Novelty:  0.09781468
p_int:  0.996989404
p_ni:  0.003010559
p_wrong:  3.7e-8
Score:  0.827
Data Source:  BioPlex,STRINGDB
TRAPPC3
Tbio
Novelty:  0.0360262
p_int:  0.995485056
p_ni:  0.004514944
Score:  0.81
Data Source:  BioPlex,STRINGDB
TRAPPC2
Tbio
Novelty:  0.02016231
p_int:  0.974631093
p_ni:  0.025368862
p_wrong:  4.5e-8
Score:  0.815
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Alzheimer disease
5
1
0
1.1
84.8
family history of Alzheimer’s disease
2
1
0
3.9
79.9
1
1
0
1.9
74.9
myeloid white cell count
1
1
1
52.3
leukocyte count
1
1
1
35.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Alzheimer disease
0
1.1
84.8
family history of Alzheimer’s disease
0
3.9
79.9
0
1.9
74.9
myeloid white cell count
1
52.3
leukocyte count
1
35.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
stathmin 4
VGNC:2453
472724
Macaque
stathmin 4
712651
Mouse
MGI:1931224
56471
Rat
RGD:69349
79423
Dog
stathmin 4
VGNC:46928
486105
Species
Name
OMA
EggNOG
Inparanoid
Chimp
stathmin 4
Macaque
stathmin 4
Mouse
Rat
Dog
stathmin 4
Publication Statistics
PubMed Score 15.77
PubMed score by year
PubTator Score 38.91
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title