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Tbio
STARD7
StAR-related lipid transfer protein 7, mitochondrial

Protein Summary
Description
May play a protective role in mucosal tissues by preventing exaggerated allergic responses.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000337288
  • ENSP00000338030
  • ENSG00000084090

Symbol
  • GTT1
  • GTT1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
1
disease perturbation
0.9
kinase perturbation
0.81
transcription factor binding site profile
0.75
microRNA
0.72


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.6   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 139   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.6   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 139   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (44)
AGFG2
Tbio
Novelty:  0.10320266
p_int:  0.999999542
p_ni:  4.58e-7
Score:  0.356
Data Source:  BioPlex,STRINGDB
NAT2
Tbio
Family:  Enzyme
Novelty:  0.00150849
p_int:  0.999999408
p_ni:  5.19e-7
p_wrong:  7.3e-8
Score:  0.351
Data Source:  BioPlex,STRINGDB
KHDC4
Tdark
Novelty:  0.47115316
p_int:  0.999970087
p_ni:  3e-8
p_wrong:  0.000029883
Score:  0.381
Data Source:  BioPlex,STRINGDB
CCDC91
Tbio
Novelty:  0.11171935
p_int:  0.999887866
p_ni:  0.000112132
p_wrong:  1e-9
Score:  0.188
Data Source:  BioPlex,STRINGDB
CRYAA
Tchem
Novelty:  0.01914081
p_int:  0.999410999
p_ni:  0.000565372
p_wrong:  0.000023629
Data Source:  BioPlex
PRKCA
Tchem
Family:  Kinase
Novelty:  0.00057611
p_int:  0.99803782
p_ni:  0.001962058
p_wrong:  1.22e-7
Score:  0.18
Data Source:  BioPlex,STRINGDB
PIGM
Tbio
Family:  Enzyme
Novelty:  0.02186069
p_int:  0.996986951
p_ni:  0.003013016
p_wrong:  3.2e-8
Score:  0.234
Data Source:  BioPlex,STRINGDB
GLTP
Tbio
Novelty:  0.01044466
p_int:  0.980286007
p_ni:  0.019713219
p_wrong:  7.74e-7
Score:  0.289
Data Source:  BioPlex,STRINGDB
AES
Tbio
Novelty:  0.00818499
p_int:  0.970700654
p_ni:  0.00291266
p_wrong:  0.026386686
Score:  0.187
Data Source:  BioPlex,STRINGDB
DOHH
Tbio
Family:  Enzyme
Novelty:  0.02313651
p_int:  0.866965911
p_ni:  0.133034088
p_wrong:  1e-9
Score:  0.187
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (5)
Glycerophospholipid biosynthesis (R-HSA-1483206)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Glycerophospholipid biosynthesis
Reactome
Metabolism
Reactome
Metabolism of lipids
Reactome
Phospholipid metabolism
Reactome
Synthesis of PC
Name
Explore in Pharos
Explore in Source
Glycerophospholipid biosynthesis
Metabolism
Metabolism of lipids
Phospholipid metabolism
Synthesis of PC
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
1
1
1
62.8
mathematical ability
1
1
1
21.5
diastolic blood pressure
1
1
1
15.8
monocyte percentage of leukocytes
1
1
1
13.6
1
1
0
2.3
4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
1
62.8
mathematical ability
1
21.5
diastolic blood pressure
1
15.8
monocyte percentage of leukocytes
1
13.6
0
2.3
4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
StAR related lipid transfer domain containing 7
VGNC:391
459411
Macaque
StAR related lipid transfer domain containing 7
704860
Mouse
MGI:2139090
99138
Rat
RGD:1307613
296128
Dog
StAR related lipid transfer domain containing 7
VGNC:46887
475744
Species
Name
OMA
EggNOG
Inparanoid
Chimp
StAR related lipid transfer domain containing 7
Macaque
StAR related lipid transfer domain containing 7
Mouse
Rat
Dog
StAR related lipid transfer domain containing 7
Publication Statistics
PubMed Score 26.60
PubMed score by year
PubTator Score 11.92
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title