ST7
Suppressor of tumorigenicity 7 protein
Protein Summary
May act as a tumor suppressor. The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
- ENST00000265437
- ENSP00000265437
- ENSG00000004866
- ENST00000393443
- ENSP00000377089
- ENST00000393451
- ENSP00000377097
- FAM4A1
- HELG
- RAY1
- HELG
- RAY1
- SEN4
- TSG7
- ETS7q
- FAM4A
- FAM4A1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
disease perturbation | 0.9 | ||
transcription factor binding site profile | 0.86 | ||
cell type or tissue | 0.76 | ||
transcription factor perturbation | 0.74 | ||
cell line | 0.7 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 34.2 (req: < 5)
Gene RIFs: 12 (req: <= 3)
Antibodies: 128 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 34.2 (req: >= 5)
Gene RIFs: 12 (req: > 3)
Antibodies: 128 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0