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Tdark
SSPO
SCO-spondin

Protein Summary
Description
Involved in the modulation of neuronal aggregation. May be involved in developmental events during the formation of the central nervous system (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000378016
  • ENSP00000485256
  • ENSG00000197558

Symbol
  • KIAA2036
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
1
pathway
0.65
tissue sample
0.61
cell type or tissue
0.56
cell line
0.48


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (0)
No protein-protein interactions found
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (9)
Defective B3GALTL causes Peters-plus syndrome (PpS) (R-HSA-5083635)

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Find Similar Targets
Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Defective B3GALTL causes Peters-plus syndrome (PpS)
Reactome
Disease
Reactome
Diseases associated with O-glycosylation of proteins
Reactome
Diseases of glycosylation
Reactome
Metabolism of proteins
Name
Explore in Pharos
Explore in Source
Defective B3GALTL causes Peters-plus syndrome (PpS)
Disease
Diseases associated with O-glycosylation of proteins
Diseases of glycosylation
Metabolism of proteins
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mosaic loss of chromosome Y measurement
2
1
2
81.2
platelet crit
1
1
1
63.1
pulse pressure measurement
1
1
1
49.5
platelet count
1
1
1
31.4
systolic blood pressure change measurement
1
1
0
73.7
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mosaic loss of chromosome Y measurement
2
81.2
platelet crit
1
63.1
pulse pressure measurement
1
49.5
platelet count
1
31.4
systolic blood pressure change measurement
0
73.7
21.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2674311
243369
Rat
RGD:1549716
474348
Dog
SCO-spondin
VGNC:46836
482788
Zebrafish
ZDB-GENE-051114-1
100036547
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
SCO-spondin
Zebrafish
Publication Statistics
PubTator Score 6.56
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title