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Tdark
SSMEM1
Serine-rich single-pass membrane protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297819
  • ENSP00000297819
  • ENSG00000165120

Symbol
  • C7orf45
  • C7orf45
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.73
PubMedID
0.62
cell type or tissue
0.49
chemical
0.41
transcription factor
0.39


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 52   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.94   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 52   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
SMAD5
Tbio
Family:  TF
Novelty:  0.00405952
p_int:  0.999980457
p_ni:  0.000019511
p_wrong:  3.2e-8
Score:  0.219
Data Source:  BioPlex,STRINGDB
CSNK1A1
Tchem
Family:  Kinase
Novelty:  0.00636472
p_int:  0.999961821
p_ni:  0.000038179
Data Source:  BioPlex
NSUN4
Tbio
Family:  Enzyme
Novelty:  0.15593771
p_int:  0.999684156
p_ni:  0.00031521
p_wrong:  6.33e-7
Score:  0.181
Data Source:  BioPlex,STRINGDB
CSNK1E
Tclin
Family:  Kinase
Novelty:  0.00891859
p_int:  0.997329797
p_ni:  0.002670203
Score:  0.518
Data Source:  BioPlex,STRINGDB
NDUFV3
Tclin
Family:  Enzyme
Novelty:  0.15352039
p_int:  0.996626415
p_ni:  0.003373585
Score:  0.169
Data Source:  BioPlex,STRINGDB
CSNK1D
Tchem
Family:  Kinase
Novelty:  0.00896935
p_int:  0.991813738
p_ni:  0.008186262
Score:  0.527
Data Source:  BioPlex,STRINGDB
HSPA8
Tchem
Novelty:  0.00081014
p_int:  0.910958111
p_ni:  0.089041889
Data Source:  BioPlex
SPCS1
Tbio
Family:  Enzyme
Novelty:  0.0731223
p_int:  0.906280355
p_ni:  0.083411997
p_wrong:  0.010307647
Score:  0.19
Data Source:  BioPlex,STRINGDB
NDUFA7
Tclin
Family:  Enzyme
Novelty:  0.16417588
p_int:  0.870286968
p_ni:  0.129712011
p_wrong:  0.000001021
Score:  0.169
Data Source:  BioPlex,STRINGDB
CKAP4
Tbio
Novelty:  0.02104039
p_int:  0.830130235
p_ni:  0.169869765
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hip circumference
1
1
1
48.5
asparaginase-induced acute pancreatitis
1
1
0
6.6
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hip circumference
1
48.5
asparaginase-induced acute pancreatitis
0
6.6
21.5
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
serine rich single-pass membrane protein 1
VGNC:14462
742321
Macaque
serine rich single-pass membrane protein 1
702497
Mouse
MGI:1922897
75647
Rat
RGD:1559502
500068
Dog
serine rich single-pass membrane protein 1
VGNC:46834
608480
Species
Name
OMA
EggNOG
Inparanoid
Chimp
serine rich single-pass membrane protein 1
Macaque
serine rich single-pass membrane protein 1
Mouse
Rat
Dog
serine rich single-pass membrane protein 1
Publication Statistics
PubMed Score 0.94
PubMed score by year
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Related Publications
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0 of 0
PMID
Year
Title