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Tbio
SSBP3
Single-stranded DNA-binding protein 3

Protein Summary
Description
May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357475
  • ENSP00000350067
  • ENSG00000157216
  • ENST00000371319
  • ENSP00000360370
  • ENST00000371320
  • ENSP00000360371

Symbol
  • SSDP
  • SSDP1
  • CSDP
  • SSDP
  • SSDP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.99
transcription factor
0.91
transcription factor binding site profile
0.91
kinase perturbation
0.76
transcription factor perturbation
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 70.4   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 118   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 70.4   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 118   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
SSBP2
Tbio
Novelty:  0.06546999
p_int:  1
Score:  0.869
Data Source:  BioPlex,STRINGDB
SSBP4
Tdark
Novelty:  0.27365687
p_int:  1
Score:  0.867
Data Source:  BioPlex,STRINGDB
LMX1B
Tbio
Family:  TF
Novelty:  0.00405645
p_int:  1
Score:  0.83
Data Source:  BioPlex,STRINGDB
ISL2
Tbio
Family:  TF
Novelty:  0.03917372
p_int:  0.999999986
p_ni:  1.3e-8
Score:  0.879
Data Source:  BioPlex,STRINGDB
LDB1
Tbio
Novelty:  0.01110112
p_int:  0.999999985
p_ni:  1.5e-8
Score:  0.986
Data Source:  BioPlex,STRINGDB
LMO1
Tbio
Novelty:  0.01670419
p_int:  0.999999965
p_ni:  3.5e-8
Score:  0.512
Data Source:  BioPlex,STRINGDB
IDI2
Tbio
Family:  Enzyme
Novelty:  0.02715208
p_int:  0.999999884
p_ni:  1.16e-7
Score:  0.86
Data Source:  BioPlex,STRINGDB
LHX6
Tbio
Family:  TF
Novelty:  0.01603143
p_int:  0.999999702
p_ni:  2.97e-7
p_wrong:  1e-9
Score:  0.741
Data Source:  BioPlex,STRINGDB
MFAP4
Tbio
Novelty:  0.02023782
p_int:  0.999999468
p_ni:  5.32e-7
Data Source:  BioPlex
LMO2
Tbio
Novelty:  0.0038279
p_int:  0.999993645
p_ni:  0.000006355
Score:  0.742
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (14)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (20)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood urea nitrogen measurement
4
4
4
88.9
TPE interval measurement
1
2
3
85.8
electrocardiography
1
1
24
80.9
triglyceride measurement
3
2
3
74.8
1
1
1
62.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood urea nitrogen measurement
4
88.9
TPE interval measurement
3
85.8
electrocardiography
24
80.9
triglyceride measurement
3
74.8
1
62.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
single stranded DNA binding protein 3
VGNC:53214
456874
Mouse
MGI:1919725
72475
Rat
RGD:621502
84354
Horse
single stranded DNA binding protein 3
VGNC:50769
100060494
Cow
single stranded DNA binding protein 3
VGNC:35308
530184
Species
Name
OMA
EggNOG
Inparanoid
Chimp
single stranded DNA binding protein 3
Mouse
Rat
Horse
single stranded DNA binding protein 3
Cow
single stranded DNA binding protein 3
Publication Statistics
PubMed Score 70.40
PubMed score by year
PubTator Score 15.98
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title