Tbio SSBP3 Single-stranded DNA-binding protein 3

Protein Summary

Description

May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region.

Uniprot Accession IDs

• Q9BWW4
• A8K0A9
• Q5T860
• Q5T861
• Q9BTM0
• Q9BWW3

Gene Name

• SSBP3

Ensembl ID

• ENST00000357475
• ENSP00000350067
• ENSG00000157216
• ENST00000371319
• ENSP00000360370
• ENST00000371320
• ENSP00000360371

Symbol

• SSDP
• SSDP1
• CSDP
• SSDP
• SSDP1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.99
transcription factor	0.91
transcription factor binding site profile	0.91
kinase perturbation	0.76
transcription factor perturbation	0.74

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 70.4   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 118   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 70.4   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 118   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0