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Tbio
SRRM2
Serine/arginine repetitive matrix protein 2

Protein Summary
Description
Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNA substrate (By similarity). Binds to RNA.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000301740
  • ENSP00000301740
  • ENSG00000167978
  • ENST00000630499
  • ENSP00000487247

Symbol
  • KIAA0324
  • SRL300
  • SRM300
  • CWF21
  • Cwc21
  • 300-KD
  • SRL300
  • SRm300
  • HSPC075
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
drug perturbation
1
hub protein
1
interacting protein
1
transcription factor binding site profile
0.89
transcription factor perturbation
0.84


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.71   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.71   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0