Tbio SRP19 Signal recognition particle 19 kDa protein

Protein Summary

Description

Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.

Uniprot Accession IDs

• P09132
• B2R4E9
• D6RCQ5
• Q05D77
• Q96FG6
• SRP19

Gene Name

• SRP19

Ensembl ID

• ENST00000282999
• ENSP00000282999
• ENSG00000153037
• ENST00000505459
• ENSP00000424870
• ENST00000515463
• ENSP00000425562

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.95
interacting protein	0.88
kinase perturbation	0.88
virus perturbation	0.83
transcription factor binding site profile	0.76

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Ribonucleoprotein / Signal Recognition Particle 19 Kda Protein

Protein / Membrane Traffic Protein / Membrane Trafficking Regulatory Protein / Signal Recognition Particle 19 Kda Protein

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Ribonucleoprotein / Signal Recognition Particle 19 Kda Protein

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.68   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 161   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.68   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0