Protein Summary
Possible splicing regulator involved in the control of cellular survival.
- ENST00000513458
- ENSP00000427401
- ENSG00000153006
- P18SRP
- SFRS12IP1
- P18SRP
- SFRS12IP1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
microRNA | 0.93 | ||
histone modification site profile | 0.88 | ||
transcription factor binding site profile | 0.75 | ||
small molecule perturbation | 0.69 | ||
disease perturbation | 0.62 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.95 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 52 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.95 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 52 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (56)
MAP1A
Novelty: 0.00660165
p_int: 0.999929366
p_ni: 0.000054045
p_wrong: 0.000016589
Score: 0.187
Data Source: BioPlex,STRINGDB
CSNK2A2
Family: Kinase
Novelty: 0.00231447
p_int: 0.998915129
p_ni: 0.001084871
Data Source: BioPlex
CSNK2A1
Family: Kinase
Novelty: 0.00187855
p_int: 0.995975348
p_ni: 0.004024652
Data Source: BioPlex
RABL6
Family: Enzyme
Novelty: 0.11501478
p_int: 0.994558908
p_ni: 0.005365033
p_wrong: 0.000076059
Score: 0.197
Data Source: BioPlex,STRINGDB
C1orf131
Novelty: 10.11904762
p_int: 0.993035334
p_ni: 0.006964666
Score: 0.188
Data Source: BioPlex,STRINGDB
FTL
Novelty: 0.00235168
p_int: 0.986202193
p_ni: 0.013797807
Score: 0.392
Data Source: BioPlex,STRINGDB
NOS1AP
Family: Enzyme
Novelty: 0.0076555
p_int: 0.981101409
p_ni: 0.018898591
Score: 0.303
Data Source: BioPlex,STRINGDB
NUP153
Novelty: 0.00696568
p_int: 0.896144971
p_ni: 0.103855029
p_wrong: 1e-9
Score: 0.175
Data Source: BioPlex,STRINGDB
KPNA5
Novelty: 0.0762372
p_int: 0.893455732
p_ni: 0.106544268
Score: 0.204
Data Source: BioPlex,STRINGDB
KPNA6
Novelty: 0.03516499
p_int: 0.877631241
p_ni: 0.122368759
Score: 0.16
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (2)
Processes (2)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations (null)
GWAS Traits (9)
Items per page:
1 – 5 of 9
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body mass index | 3 | 3 | 3 | 71.4 | |||||
1 | 1 | 0 | 1.4 | 46.9 | |||||
cognitive function measurement | 3 | 1 | 3 | 45.7 | |||||
self reported educational attainment | 1 | 1 | 1 | 44.2 | |||||
systolic blood pressure | 1 | 1 | 1 | 38.8 | |||||
Items per page:
1 – 5 of 9
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body mass index | 3 | 71.4 | |||||
0 | 1.4 | 46.9 | |||||
cognitive function measurement | 3 | 45.7 | |||||
self reported educational attainment | 1 | 44.2 | |||||
systolic blood pressure | 1 | 38.8 | |||||
Find similar targets by:
IDG Resources
Orthologs (12)
1 – 5 of 12
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | SREK1 interacting protein 1 | VGNC:7156 | 743558 | |||||
Macaque | SREK1 interacting protein 1 | 695436 | ||||||
Mouse | MGI:1914538 | 67288 | ||||||
Rat | RGD:2323713 | 100362980 | ||||||
Dog | SREK1 interacting protein 1 | VGNC:46798 | 609639 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | SREK1 interacting protein 1 | |||||
Macaque | SREK1 interacting protein 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | SREK1 interacting protein 1 | |||||
Publication Statistics
PubMed Score 0.95
PubMed score by year
PubTator Score 0.73
PubTator score by year
Related Publications
Text Mined References (5)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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