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Tbio
SRBD1
S1 RNA-binding domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263736
  • ENSP00000263736
  • ENSG00000068784
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
1
histone modification site profile
0.81
transcription factor binding site profile
0.7
transcription factor perturbation
0.68
cell line
0.58


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.69   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 113   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.69   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 113   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (87)
RCAN1
Tbio
Novelty:  0.0030009
p_int:  0.999946791
p_ni:  0.000053205
p_wrong:  4e-9
Score:  0.694
Data Source:  BioPlex,STRINGDB
RPS16
Tbio
Novelty:  0.00261983
p_int:  0.999826968
p_ni:  0.000173032
Data Source:  BioPlex
MYL6
Tbio
Novelty:  0.00594485
p_int:  0.999742718
p_ni:  0.000257282
p_wrong:  1e-9
Data Source:  BioPlex
SCYL3
Tbio
Family:  Kinase
Novelty:  0.13735583
p_int:  0.999522943
p_ni:  0.000477057
Data Source:  BioPlex
GSK3A
Tclin
Family:  Kinase
Novelty:  0.00925708
p_int:  0.998926565
p_ni:  0.000062975
p_wrong:  0.00101046
Score:  0.697
Data Source:  BioPlex,STRINGDB
ZNF777
Tdark
Family:  TF
Novelty:  1.20195224
p_int:  0.997329053
p_ni:  0.002670947
Data Source:  BioPlex
TRIM44
Tbio
Novelty:  0.00483553
p_int:  0.99571541
p_ni:  0.004284588
p_wrong:  1e-9
Data Source:  BioPlex
ARHGAP22
Tbio
Family:  Enzyme
Novelty:  0.13037853
p_int:  0.992126377
p_ni:  0.007869226
p_wrong:  0.000004397
Score:  0.524
Data Source:  BioPlex,STRINGDB
MECP2
Tchem
Family:  TF
Novelty:  0.00051767
p_int:  0.990937644
p_ni:  0.009062162
p_wrong:  1.94e-7
Data Source:  BioPlex
CROCC
Tbio
Novelty:  0.03718561
p_int:  0.988469515
p_ni:  0.011529773
p_wrong:  7.12e-7
Score:  0.183
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
2
2
88.3
hematocrit
1
1
1
49.5
hemoglobin measurement
1
1
1
44.2
platelet crit
1
1
1
33.1
1
1
0
2.8
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
88.3
hematocrit
1
49.5
hemoglobin measurement
1
44.2
platelet crit
1
33.1
0
2.8
31.4
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
S1 RNA binding domain 1
VGNC:383
738521
Mouse
MGI:1925836
78586
Rat
RGD:1562788
301665
Dog
S1 RNA binding domain 1
VGNC:46790
611842
Horse
S1 RNA binding domain 1
VGNC:23570
100068692
Species
Name
OMA
EggNOG
Inparanoid
Chimp
S1 RNA binding domain 1
Mouse
Rat
Dog
S1 RNA binding domain 1
Horse
S1 RNA binding domain 1
Publication Statistics
PubMed Score 5.69
PubMed score by year
PubTator Score 2.71
PubTator score by year
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Related Publications
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PMID
Year
Title