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Tbio
SPRN
Shadow of prion protein

Protein Summary
Description
Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000414069
  • ENSP00000433712
  • ENSG00000203772

Symbol
  • SHO
  • SHO
  • SHADOO
  • bA108K14.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.86
cellular component
0.74
cell type or tissue
0.57
tissue sample
0.57
cell line
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 48.09   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 104   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 48.09   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 104   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0