SPPL2B
Signal peptide peptidase-like 2B
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cellular component | 0.85 | ||
histone modification site profile | 0.76 | ||
tissue | 0.67 | ||
kinase perturbation | 0.66 | ||
transcription factor binding site profile | 0.64 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Death Receptor Signalling | ||||
Reactome | Regulation of TNFR1 signaling | ||||
Reactome | Signal Transduction | ||||
Reactome | TNF signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Death Receptor Signalling | ||||
Regulation of TNFR1 signaling | ||||
Signal Transduction | ||||
TNF signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body mass index | 2 | 2 | 2 | 72.8 | |||||
pulse pressure measurement | 1 | 1 | 1 | 64 | |||||
self reported educational attainment | 1 | 1 | 1 | 44.2 | |||||
body height | 1 | 1 | 1 | 35 | |||||
age-related hearing impairment | 1 | 1 | 0 | 5.9 | 30.2 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body mass index | 2 | 72.8 | |||||
pulse pressure measurement | 1 | 64 | |||||
self reported educational attainment | 1 | 44.2 | |||||
body height | 1 | 35 | |||||
age-related hearing impairment | 0 | 5.9 | 30.2 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | signal peptide peptidase like 2B | VGNC:13515 | 750100 | |||||
Mouse | MGI:1920468 | 73218 | ||||||
Rat | RGD:1308556 | 362828 | ||||||
Dog | signal peptide peptidase like 2B | VGNC:46759 | 485071 | |||||
Cow | signal peptide peptidase like 2B | VGNC:35235 | 504285 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | signal peptide peptidase like 2B | |||||
Mouse | ||||||
Rat | ||||||
Dog | signal peptide peptidase like 2B | |||||
Cow | signal peptide peptidase like 2B | |||||
PMID | Year | Title |
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