Tdark SPIN2A Spindlin-2A

Protein Summary

Description

May be involved in the regulation of cell cycle progression (By similarity). Exhibits H3K4me3-binding activity (PubMed:29061846). This gene encodes one of three members of the DXF34 gene family, located in a 100-kb region of chromosome Xp11.21. [provided by RefSeq, Nov 2009]

Uniprot Accession IDs

• Q99865
• O75650
• Q6IPW2
• Q9UJJ0

Gene Name

• SPIN2A

Ensembl ID

• ENST00000374906
• ENSP00000364041
• ENSG00000147059
• ENST00000374908
• ENSP00000364043

Symbol

• DXF34
• SPIN2
• DXF34
• SPIN2
• TDRD25
• dJ323P24.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.63
tissue sample	0.56
tissue	0.48
cell line	0.44
chemical	0.41

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.84   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 48   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.84   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 48   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0